Publications by authors named "Christian Zwanzger"
Texture Analysis of the Apparent Diffusion Coefficient Focused on Contrast-Enhancing Lesions in Predicting Survival for Bevacizumab-Treated Patients with Recurrent Glioblastoma.
Antonio Lopez-Rueda Josep Puig Santiago Thió-Henestrosa Javier Luis Moreno-Negrete Christian Zwanzger
Cancers (Basel)
June 2023
Article Synopsis
- Glioblastoma often recurs after treatment, and this study investigates how magnetic resonance texture analysis (MRTA) can predict survival outcomes for patients treated with bevacizumab.
- A retrospective analysis of 33 patients revealed that certain radiomic features, such as major axis length, 2D diameter, and skewness, were linked to longer progression-free and overall survival.
- Preliminary findings indicate that MRTA could serve as a valuable tool for predicting survival, assisting in clinical decision-making for glioblastoma treatment.
Objectives: The purpose of this study was to analyze the new combined indicators on noncontrast computed tomography (NCCT) to predict functional outcome at discharge, compared to previously individual radiological NCCT signs.
Methods: Patients with spontaneous intracerebral hemorrhage (ICH) who underwent baseline CT scan were retrospectively analyzed. Black hole (BH) sign, blend sign (BS), island sign (IS), swirl sign (SwS), Barras classification, any hypodensity, any irregularity, and two combined novel indicators-Combined Barras Total Score (CBTS) and Hematoma Maturity Score-were assessed independently by two radiologists blinded to clinical information.