Older adults are among those most vulnerable to harm in disasters, such as hurricanes and wildfires. Nursing homes and other Medicare providers are subject to federal requirements to develop detailed disaster plans. However, millions of older adults receive care at home from non-Medicare providers who are under federal disaster preparedness rules that are less prescriptive than Medicare rules and subject to state interpretation.
View Article and Find Full Text PDFAims: Primary cilia play an important role in the regulation of cell signalling pathways and are thought to have a role in cancer but have seldom been studied in human cancer samples.
Methods: Primary cilia were visualised by dual immunofluorescence for anti-CROCC (ciliary rootlet coiled-coil) and anti-tubulin in a range of human cancers (including carcinomas of stomach, pancreas, prostate, lung and colon, lobular and ductal breast cancers and follicular lymphoma) and in matched normal tissue (stomach, pancreas, lung, large and small intestines, breast and reactive lymph nodes) samples using a tissue microarray; their frequency, association with proliferation, was measured by Ki-67 staining and their structure was analysed.
Results: Compared with normal tissues, primary cilia frequency was significantly elevated in adenocarcinoma of the lung (2.