Overall Survival among Patients with Cancer and Pressure Injury and Its Association with Braden Scale Score.

The overall survival (OS) of hospitalized cancer patients with pressure injury (PI) has not been studied in a large cohort. To assess risk factors associated with OS of hospitalized cancer patients with PI. After IRB approval, charts of 445 hospitalized cancer patients with PI were reviewed.

Oncogenic Recruits an Expansive Transcriptional Network through Mutant p53 to Drive Pancreatic Cancer Metastasis.

Pancreatic ductal adenocarcinoma (PDAC) is almost uniformly fatal and characterized by early metastasis. Oncogenic mutations prevail in 95% of PDAC tumors and co-occur with genetic alterations in the tumor suppressor in nearly 70% of patients. Most alterations are missense mutations that exhibit gain-of-function phenotypes that include increased invasiveness and metastasis, yet the extent of direct cooperation between effectors and mutant p53 remains largely undefined.

Symptom Burden and Functional Gains in a Cancer Rehabilitation Unit.

Background/aims: To determine if there is a relationship between patient symptoms and functional improvement on inpatient rehabilitation.

Methods: Retrospective review of medical records at an American tertiary referral-based cancer center of all patients admitted to an inpatient rehabilitation unit between 3/1/2013-5/20/2013. Main outcome measures included the Edmonton Symptom and Assessment Scale (ESAS) and Functional Independence Measure (FIM).