Publications by authors named "Christian Robert Andres"
Article Synopsis
- The study investigates the role of the ubiquitin pathway in amyotrophic lateral sclerosis (ALS) by analyzing genes associated with this pathway in 176 ALS patients.
- Through next-generation sequencing, researchers identified both known and new pathogenic variants in these genes, highlighting the significance of the ubiquitin system in ALS.
- One notable finding was the role of the NEDL1 gene, which encodes a protein linked to increased cell death and mislocalization of TDP-43, a protein critical to ALS pathology, suggesting a need for further research on NEDL1’s involvement in the disease.
Background: Glomerular filtration rate (GFR) measurement is a major issue in kidney transplant recipients for clinicians. GFR can be determined by estimating the plasma clearance of iohexol, a nonradiolabeled compound. For practical and convenient application for patients and caregivers, it is important that a minimal number of samples are drawn.
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