Effect of incomplete parathyroidectomy preserving entire parathyroid glands on renal graft function.

Hypothesis: Parathyroidectomy (PT) corrects tertiary hyperparathyroidism in patients who have received renal grafts but can result in deterioration of renal function.

Objective: To compare different surgical procedures for their effect on renal function and efficacy to cure tertiary hyperparathyroidism.

Design: A retrospective cohort study.

FTY720 improves survival after transient ischemia and reperfusion of the hind limbs.

Background: Ischemia and reperfusion (I/R) damage involves adhesion and transmigration of lymphocytes and neutrophils. FTY720 is an immunosuppressive agent that reduces the number of neutrophils and monocytes in peripheral blood as well as tissue lymphocyte infiltration. This study investigated the effect of FTY720 during hind limb I/R.

Peri-operative filtration of disseminated cytokeratin positive cells in patients with colorectal liver metastasis.

Background: Liver resection is the only potential cure for patients with colorectal liver metastasis. However, more than 30% of patients will develop tumour recurrence, probably caused by tumour cells disseminated before or during surgery. As prevention of cell dissemination is barely obtainable, alternative concepts have to be discussed.