In this work, we introduce an extension of the linear elastic tensor-mass method allowing fast computation of non-linear and visco-elastic mechanical forces and deformations for the simulation of biological soft tissue. We aim at developing a simulation tool for the planning of cryogenic surgical treatment of liver cancer. Percutaneous surgery simulation requires accurate modelling of the mechanical behaviour of soft tissue, and previous experimental characterizations have shown that linear elasticity is only a coarse approximation of the real properties of biological tissues.
View Article and Find Full Text PDFPurpose: This phase I study was designed to demonstrate the feasibility, safety, efficacy and predictability of percutaneous cryosurgery, guided under magnetic resonance (MR) imaging, in the treatment of invasive breast carcinoma.
Patients And Methods: Under the guidance of near-real-time T1-weighted FSE images of a 0.5-T open-configuration MR system, percutaneous cryosurgery was performed in 25 patients with operable invasive breast carcinoma, 4 weeks prior to their scheduled mastectomy.
IEEE Trans Med Imaging
January 2004
This paper presents a newly developed method to estimate, in magnetic resonance (MR) images, the temperatures reached within the volume of an iceball produced by a cryogenic probe. Building on the direct measurements of the MR signal intensity and its correlation with independent temperature variations at the phase transition from liquid to solid, the thermal information embedded in the images was accessed. The volume and diameter of the growing iceball were estimated from a time series of MR images.
View Article and Find Full Text PDFThe present study was undertaken to measure the gain observed in the liver-to-tumor contrast of perioperative images when using mangafodipir trisodium, a liver-specific contrast agent, during percutaneous cryosurgery of the liver performed under the guidance of magnetic resonance images. Retrospective quantitative analyses of MR images were performed on eleven patients having a total of 30 liver tumors treated by MR-guided percutaneous cryosurgery. An initial group of four patients were treated with no contrast agent, and was compared with a second group of 7 patients who received an intravenous injection of 5 microM/kg of mangafodipir for their cryosurgery.
View Article and Find Full Text PDFJ Magn Reson Imaging
July 2003
Purpose: To compare the acromiohumeral distance (AHD) of both shoulders in subjects with a unilateral shoulder impingement syndrome (SIS) and healthy subjects in a seated position during free shoulder movements of large amplitude.
Materials And Methods: Using a 0.5-Tesla SIGNA-SP/i trade mark open-configuration magnetic resonance imaging (MRI) system, the AHD was measured at several arm positions, in a standardized seated position.