Publications by authors named "Christian Jensen"

We provide efficient support for applications that aim to continuously find pairs of similar sets in rapid streams, such as Twitter streams that emit tweets as sets of words. Using a sliding window model, the top- result changes as new sets enter the window or existing ones leave the window. Specifically, when a set arrives, it may form a new top- result pair with any set already in the window.

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  • The study aimed to determine the links between MRI measurements of the membranous urethra and prostate volume with urinary continence after robot-assisted radical prostatectomy (RARP).
  • It involved 100 patients, examining MRI scans before and a year after surgery, measuring anatomical features and assessing urinary function using a standardized questionnaire.
  • Results showed that longer membranous urethral lengths (MUL) before and after surgery were positively associated with higher continence rates, while larger prostate volumes were linked to increased urinary incontinence.
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Background: There is a lack of evidence concerning recurrent patterns and treatment of repeat recurrences for surgically treated renal cell carcinoma (RCC). Thus, the objective was to describe patterns of recurrences and subsequent treatments in patients with recurrent RCC.

Patients And Methods: We identified 525 patients who received surgical treatment for RCC at our institution in 2010-2015.

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  • This study analyzed the effects of age on outcomes for patients undergoing medial unicompartmental knee arthroplasty (mUKA), revealing that contemporary practices no longer limit eligibility based on age.
  • A total of 782 patients were evaluated, showing significant improvements in knee function across all age groups after surgery, with no notable differences in the overall outcomes based on age.
  • However, patients aged 55 to < 65 years experienced less improvement in specific measures of joint awareness and participation, but overall satisfaction was high across all age categories, supporting the current approach of not using age as a restriction for mUKA.
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  • - The study aimed to assess day-case surgery success rates for primary total hip arthroplasty (THA), total knee arthroplasty (TKA), and medial unicompartmental knee arthroplasty (mUKA), investigating the reasons for patients not being discharged on the same day despite eligibility.
  • - Conducted over a year with 6,142 patients, the study found that 34% of THA and TKA patients and 52% of mUKA patients were eligible for day-case surgery, with mUKA showing the highest success rates (72%) when surgeries were completed before 1:00 pm.
  • - Key reasons for day-case failures included issues with patient mobilization,
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  • Noise alerts in intrusion detection systems can overwhelm analysts and disrupt operations, often triggered by routine software tasks or user activities.
  • This paper introduces a method to minimize these noise alerts by identifying frequent alerts based on their occurrence rates, suggesting that simpler algorithms can effectively address the problem.
  • The proposed Apriori-based approach demonstrated a significant reduction in noise alerts, filtering over 40% of alerts with a minimum occurrence threshold of 70%, and over 90% for certain alert categories based on real customer data from a Danish NDR solution.
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Background: Diabetes distress refers to the negative emotional reaction to living with the demands of diabetes; it occurs in >40% of adults with type 1 diabetes (T1D). However, no interventions to reduce diabetes distress are specifically designed to be an integral part of diabetes care.

Objective: This study aims to modify and adapt existing evidence-based methods into a nurse-led group intervention to reduce diabetes distress among adults with T1D and moderate to severe diabetes distress.

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Background: CV-NCOV-005 was conducted to generate additional safety and immunogenicity data for the former CVnCoV SARS-CoV-2 mRNA vaccine candidate in healthcare workers (HCW).

Methods: Randomised, observer blinded, placebo-controlled, phase 3 trial performed at the University Medical Center Mainz, Germany. HCWs aged ≥18 years with no history of SARS-CoV-2 infection/positive serology were randomly assigned to receive two doses of CVnCoV, or two doses of placebo (0.

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Importance: Advances in the treatment of childhood cancer have significantly improved survival rates, with more than 80% of survivors reaching adulthood. However, gonadotoxic cancer treatments endanger future fertility, and prepubertal males have no option to preserve fertility by sperm cryopreservation. In addition, boys with cryptorchidism are at risk of compromised fertility in adulthood.

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Background And Objective: It is considered standard for authors of scientific papers to provide access to their raw data. The purpose of this study was to investigate data availability statements (DAS) and the actual availability of data in urology.

Methods: The DAS policies of the top ten urology journals were retrieved.

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  • The study explores the link between pain catastrophizing (a psychological condition) and acute pain levels after unicompartmental knee arthroplasty (UKA), contrasting with prior research on total knee arthroplasty.
  • Conducted as a prospective observational study, it involved 125 UKA patients, evaluating their postoperative pain through a diary at various intervals after surgery.
  • Findings revealed that while 31% were predicted high-pain responders, preoperative pain catastrophizing did not correlate significantly with higher pain during the first week post-surgery.
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Purpose: Platelet-rich plasma (PRP) as a regenerative therapy has gained interest in the field of andrology for the treatment of erectile dysfunction (ED) and Peyronie's disease (PD). This systematic review aims to critically evaluate the current evidence on the use of PRP for these conditions.

Methods: We performed a systematic literature search according to the PRISMA guidelines using PubMed and Scopus databases in December 2023.

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  • * A prospective study involved 2,756 patients, where 37% were eligible for same-day discharge based on specific criteria, and 21% were actually discharged that day, marking a significant increase compared to pre-pandemic discharge rates.
  • * The findings suggest that outpatient procedures are feasible in public healthcare settings, with expectations that success rates will improve as hospitals gain more experience with the protocol.
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Background: The association between type 2 diabetes and electrocardiographic (ECG) markers are incompletely explored and the dependence on diabetes duration is largely unknown. We aimed to investigate the electrocardiographic (ECG) changes associated with type 2 diabetes over time.

Methods: In this cross-sectional study, we matched people with type 2 diabetes 1:1 on sex, age, and body mass index with people without diabetes from the general population.

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Purpose: Endophytic renal cancer treatment is a challenge. Due to difficulties in endophytic tumor visualization during surgical extirpation, image-guided percutaneous cryoablation (PCA) is an attractive alternative. The minimally invasive nature of PCA makes it favorable for comorbid patients as well as patients in which surgery is contraindicated.

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  • The study aimed to determine the proportion of hip and knee arthroplasty patients eligible for day-case surgery in Denmark and to see if eligibility changed over time.
  • Researchers analyzed data from the Danish National Patient Register covering patients from January 2010 to March 2020, finding that 48% of patients were eligible for day-case surgery, with a slight decline in eligibility over the years.
  • Despite nearly half of patients qualifying for same-day discharge, only about 8% were actually discharged on the day of surgery in 2019, indicating a significant opportunity for increasing day-case procedures.
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Background: Testicular microlithiasis is the presence of small calcifications in the testicular parenchyma. The association between testicular microlithiasis and germ cell neoplasia in situ, a precursor to testicular cancer, is still unclear.

Objectives: To determine the incidence of germ cell neoplasia in situ in men with testicular microlithiasis and evaluate the indication for testicular biopsy according to risk factors in the form of male infertility/reduced semen quality, testicular atrophy, and history of cryptorchidism.

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A surge in gonorrhoea in Denmark has occurred since 2022, a 46% increase from 2021. National surveillance, leveraging mandatory reporting and epidemiological data, highlights three distinct clades linked to heterosexual transmission. Despite the rise, these exhibit high susceptibility, contrasting MSM-associated strains.

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Objective: To explore how the use of the ProPep® Nerve Monitoring System (ProPep Surgical, Austin, TX, USA) for intraoperative specific sparing of the pudendal nerve fibres influences postoperative functional outcomes after unilateral nerve-sparing (UNS) or non-nerve-sparing (NNS) robot-assisted radical prostatectomy (RARP).

Patients And Methods: We randomised 100 men undergoing UNS or NNS RARP to ProPep nerve monitoring during RARP (intervention) or standard of care RARP (control). Functional outcomes were assessed at 3, 6, and 12 months using the International Consultation on Incontinence Questionnaire Short Form (ICIQ-SF), the International Prostate Symptom Score, the Danish Prostate Symptom Score, the International Index of Erectile Function, the Erection Hardness Scale, and 24-h pad tests.

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We assessed the seroepidemiology of SARS-CoV-2 infection and the incidence of coronavirus disease 2019 (COVID-19) before and during the rollout of COVID-19 vaccines, in a prospective observational cohort study on healthcare workers (HCWs) in a large tertiary hospital in Mainz, Germany. Antibody status was assessed during six visits between September 2020 and February 2022. Self-reported symptoms were collected using a smartphone application; symptomatic HCWs were tested using real-time polymerase chain reaction (RT-PCR) assays for SARS-CoV-2.

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Treatment with Phosphodiesterase Type 5 inhibitors (PDE5is) has shown promise in managing Peyronie's disease (PD) during its active phase. In a retrospective cohort study of 133 PD patients, we compared daily PDE5i treatment (sildenafil 25 mg or tadalafil 5 mg) in Group 1 (n = 101) to no treatment in Group 2 (n = 32). The mean age ± SD was 58.

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Objectives: We aimed to determine the incidence rate, pathogen composition, and risk factors, particularly airflow limitation, associated with bacterial respiratory infection and pneumonia in a prospective cohort of well-treated people with HIV (PWH) between 2015-2021.

Methods: We included 1007 PWH from the Copenhagen Comorbidity in HIV infection (COCOMO) study. Spirometry was performed at inclusion.

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