Publications by authors named "Christian Ja Sigrist"
Article Synopsis
- Integrin could potentially serve as an alternative receptor for SARS-CoV-2, influencing how the virus spreads and causes disease.
- The spike protein of SARS-CoV-2 has a unique RGD motif that specifically binds to integrins, a feature not found in other coronaviruses.
- This integrin-binding area is located near the ACE2 receptor-binding site on the spike protein, suggesting that targeting integrin interactions may be a useful therapeutic strategy that warrants further experimental investigation.
