Publications by authors named "Christian Heinrich"

We have previously reported a new design for drift-free liquid-crystal polarization modulators (LCMs) based on liquid-crystal variable retarders (LCVRs). Here, we study their performance on Stokes and Mueller polarimeters. LCMs have polarimetric responses similar to LCVRs and can be used as temperature-stable alternatives to many LCVR-based polarimeters.

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We report a new design for temperature-stable polarization modulators. Each modulator is composed of two liquid crystal variable retarders (LCVRs) positioned in such a way that their temperature drifts mutually compensate. We propose a model for the temperature-dependent polarization response of LCVRs, which permits us to establish expressions for the operating point of the system and for its accessible retardance range.

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A better understanding of tumor development is crucial for treating cancer. Polarimetric imaging is an interesting alternative for monitoring subcutaneous tumors as it is non-invasive. In this study, a Mueller spectro-polarimeter is used to monitor tumor development on mice injected with non-pigmented breast cancer cells or with pigmented murine melanoma cells.

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Thus far, emergency calls are answered by human operators who interview the calling person in order to obtain all relevant information. In the near future-based on the Internet of (Medical) Things (IoT, IoMT)-accidents, emergencies, or adverse health events will be reported automatically by smart homes, smart vehicles, or smart wearables, without any human in the loop. Several parties are involved in this communication: the alerting system, the rescue service (responding system), and the emergency department in the hospital (curing system).

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Human brain connectome studies aim to both explore healthy brains, and extract and analyze relevant features associated with pathologies of interest. Usually this consists of modeling the brain connectome as a graph and using graph metrics as features. A fine brain description requires graph metrics computation at the node level.

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Mueller polarimetry is a powerful imaging modality that has been successfully applied to various application fields. Decomposition of Mueller matrices in elementary components is classically considered in order to unfold complex physical phenomena taking place in probed samples or scenes. In this context, the generalized polar decomposition, also known as Lu and Chipman decomposition, plays a prominent role.

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Mueller polarimetry is increasingly recognized as a powerful modality in biomedical imaging. Nevertheless, principled statistical analysis procedures are still lacking in this field. This paper presents a complete pipeline for polarimetric bioimages, with an application to ex vivo cervical precancer detection.

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In case of diarrhea calves are treated with oral rehydration solutions (ORS), which are known to increase abomasal pH and inhibit milk clotting in vitro. Nevertheless, recent studies have shown that ORS with HCO3(-) ≤ 62 mmol/L do not interfere with abomasal milk clotting in healthy calves. However, in diarrheic calves, feeding ORS and milk simultaneously may disturb abomasal curd formation and exacerbate diarrhea due to faster abomasal passage of ingesta.

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This study investigates rhythmic features based on the short-time energy function of speech signals with the aim of finding robust, speaker-independent features that indicate speaker intoxication. Data from the German Alcohol Language Corpus, which comprises read, spontaneous, and command&control speech uttered by 162 speakers of both genders and various age groups when sober and intoxicated, were analyzed. Energy contours are compared directly (Root Mean Squared Error, statistical correlation, or the Euclidean distance in the spectral space of the contour) and by parameterization of the contour using the Discrete Cosine Transform (DCT) and the first and second moments of the lower DCT spectrum.

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This article addresses the estimation of polarization signatures in the Mueller imaging framework by non-local means filtering. This is an extension of previous work dealing with Stokes signatures. The extension is not straightforward because of the gap in complexity between the Mueller framework and the Stokes framework.

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Conventional estimation techniques of Stokes images from observed radiance images through different polarization filters suffer from noise contamination that hampers correct interpretation or even leads to unphysical estimated signatures. This paper presents an efficient restoration technique based on nonlocal means, permitting accurate estimation of smoothly variable polarization signatures in the Stokes image while preserving sharp transitions. The method is assessed on simulated data as well as on real images.

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Human brain networks have topological properties in common with many other complex systems, prompting the following question: what aspects of brain network organization are critical for distinctive functional properties of the brain, such as consciousness? To address this question, we used graph theoretical methods to explore brain network topology in resting state functional MRI data acquired from 17 patients with severely impaired consciousness and 20 healthy volunteers. We found that many global network properties were conserved in comatose patients. Specifically, there was no significant abnormality of global efficiency, clustering, small-worldness, modularity, or degree distribution in the patient group.

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This study investigates long-term features and utterance contours of fundamental frequency (f0) derived from the German Alcohol Language Corpus. The corpus comprises read, spontaneous, and command&control speech uttered by 148 speakers of both genders and various age groups when sober and intoxicated. f0 median, f0 range, and f0 contours are analyzed for intoxication and interactions with gender and age.

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In the case of head trauma, elongation of axons is thought to result in brain damage and to lead to Diffuse Axonal Injuries (DAI). Mechanical parameters have been previously proposed as DAI metric. Typically, brain injury parameters are expressed in terms of pressure, shearing stresses or invariants of the strain tensor.

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A Bayesian approach for joint restoration and segmentation of polarization encoded images is presented with emphasis on both physical admissibility and smoothness of the solution. Two distinct models for the sought polarized radiances are used: (i) the polarized light at each site of the image is described by its Stokes vector, which directly follows a mixture of truncated Gaussians, explicitly assigning zero probability to inadmissible configurations and (ii) polarization at each site is represented by the coherency matrix, which is parameterized by a set of variables assumed to be generated by a spatially varying mixture of Gaussians. Application on real and synthetic images using the proposed methods assesses the pertinence of the approach.

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This paper introduces a complete methodology for abdominal sounds analysis, from signal acquisition to statistical data analysis. The goal is to evaluate if and how phonoenterograms can be used to detect different functioning modes of the normal gastrointestinal tract, both in terms of localization and of time evolution during the digestion. After the description of the acquisition protocol and the employed instrumentation, several signal processing steps are presented: wavelet denoising and segmentation, artifact suppression, and source localization.

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Image registration aims at estimating a consistent mapping between two images. Common techniques consist in choosing arbitrarily one image as a reference image and the other one as a floating image, thus leading to the estimation of inconsistent mappings. We present a symmetric formulation of the registration problem that maps the two images in a common coordinate system halfway between them.

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This correspondence addresses the inversion of 3-D transformation fields, which is a problem that typically arises in image warping problems. A topology preserving parametric B-spline-based representation of the deformation field is considered. Topology preservation ensures that the transformation is a one-to-one mapping and consequently that it is invertible.

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In this paper, we extend to the Mueller imaging framework a formerly introduced Bayesian approach dealing with polarimetric data reduction and robust clustering of polarization encoded images in the piecewise constant case. The extension was made possible thanks to a suitable writing of the observation model in the Mueller context that relies on the system's coherency matrix and Cholesky decomposition such that the admissibility constraints are easily captured. This generalization comes at the cost of nonlinearity with respect to the parameters that have to be estimated.

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In this paper, we introduce a general Bayesian approach to estimate polarization parameters in the Stokes imaging framework. We demonstrate that this new approach yields a neat solution to the polarimetric data reduction problem that preserves the physical admissibility constraints and provides a robust clustering of Stokes images in regard to image noises. The proposed approach is extensively evaluated by using synthetic simulated data and applied to cluster and retrieves the Stokes image issuing from a set of real measurements.

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Background: Prognosis of esophageal cancer is poor despite curative surgery. The chemokine receptor CXCR4 has been proposed to distinctly contribute to tumor growth, dissemination and local immune escape in a limited number of malignancies. The aim of our study was to evaluate the role of CXCR4 in tumor spread of esophageal cancer with a differentiated view of the two predominant histologic types--squamous cell and adenocarcinoma.

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This paper deals with topology preservation in three-dimensional (3-D) deformable image registration. This work is a nontrivial extension of, which addresses the case of two-dimensional (2-D) topology preserving mappings. In both cases, the deformation map is modeled as a hierarchical displacement field, decomposed on a multiresolution B-spline basis.

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