Recurrence of Cholesteatoma - A Retrospective Study Including 1,006 Patients for More than 33 Years.

 Cholesteatomas are benign tumors consisting of skin, and growing inside a retraction pocket in the tympanic membrane. Cholesteatomas can occupy the entirety of the middle ear, and are known for their osteolytic capabilities. Surgery is the only curative treatment for cholesteatomas.

Postoperative infections following cochlear implant surgery.

Introduction: The aim of this study was to report the frequency and management of postoperative wound infections and to investigate bacteriology and biofilm formation following 653 consecutive cochlear implantations in adults.

Methods: A retrospective file review of 653 consecutive adult cochlear implantations between 1994 and 2015 at the Department of Otorhinolaryngology at Odense University Hospital. A reporting consensus was used to classify infections.

Refixation Saccades with Normal Gain Values: A Diagnostic Problem in the Video Head Impulse Test: A Case Report.

Refixation saccades with normal gain value occur more frequently with increasing age. The phenomenon has also been observed in different vestibular disorders. In this case, we present a young male with normal gain value and refixation saccades tested with the video head impulse test (vHIT) the day after his cochlear implantation.

Bone-anchored hearing aids are effective and associated with a high degree of satisfaction.

Introduction: The objective of this study was to evaluate patients' satisfaction with bone-anchored hearing aids (BAHA).

Methods: This study was retrospective and based on a postal questionnaire. The study sample consisted of patients undergoing surgery at Odense University Hospital in the 1992-2013-period.

Changes in salivary secretion and sense of taste following cochlear implantation: a prospective study.

Conclusion: A set of methods for evaluating changes in salivary secretion and sense of taste following cochlear implantation (CI) was applied and tested. No association between implantation and objectively assessed sense of taste was found. However, a statistically significant decrease in non-stimulated salivary flow on the day after surgery was found.

The impact of ventilation tubes in otitis media on the risk of cholesteatoma on a national level.

Objective: To estimate the impact of treatment with middle ear ventilation tube insertion (VTI) in children with otitis media (OM) on the risk of cholesteatoma on a national level.

Methods: Data were obtained from the Danish National Patient Register, the National Health Service Register and Statistics Denmark. Cumulative incidence proportions were estimated by the Kaplan-Meier method and hazard ratios with Cox regression analysis.

Quality-of-Life Differences among Diagnostic Subgroups of Children Receiving Ventilating Tubes for Otitis Media.

Objective: The pathological picture may differ considerably between diagnostic subgroups of children with otitis media receiving ventilating tubes. The aims of this study are to investigate differences in quality of life among diagnostic subgroups of children treated with ventilating tubes and to investigate possible predictors for clinical success.

Study Design: Longitudinal observational study.

Cholesteatoma in Danish children - a national study of changes in the incidence rate over 34 years.

Objective: To describe temporal trends in the incidence rate of surgically treated middle ear cholesteatoma in Danish children from 1977 to 2010.

Methods: Data on surgically treated middle ear cholesteatoma was drawn from the Danish National Patient Register. A change in incidence rate over time was examined using Poisson regression analysis, while the cumulative incidence proportion was estimated using life-tables.

Cholesteatoma risk in 8,593 orofacial cleft cases and 6,989 siblings: A nationwide study.

Objectives/hypothesis: To estimate the risk of surgically treated middle ear cholesteatoma in individuals with a nonsyndromic orofacial cleft and in their siblings compared with the general population.

Study Design: Historical cohort study.

Methods: Using the unique civil registration number for linkage, data from three national registers were used for the Danish 1936-2009 birth cohorts.

Increasing rate of middle ear ventilation tube insertion in children in Denmark.

Objective: To study the incidence rates of middle ear ventilation tube insertion in children aged 0 to 15 years in Denmark from 1997 to 2010.

Methods: Using two national registers, the Danish National Health Service Register and the Danish National Patient Register, practically all cases of middle ear ventilation tube insertion performed in Denmark in the period were identified. A possible change in incidence rate over time was examined using Poisson regression analysis, while the cumulative incidence proportion was estimated using life-tables.

Caregiver Quality of Life and Daily Functioning in Relation to Ventilating Tube Treatment.

Objective: Caregiver quality of life and daily functioning may improve after ventilating tube treatment in children with otitis media. The aims of this study are to assess possible changes in caregiver quality of life and daily functioning in relation to ventilating tube treatment and to investigate possible predictors for clinical success.

Study Design: Longitudinal observational study.

Otitis Media and Caregiver Quality of Life: Psychometric Properties of the Modified Danish Version of the Caregiver Impact Questionnaire.

Objective: Otitis media in children may have a considerable impact on caregiver quality of life. The disease-specific Caregiver Impact Questionnaire is designed to assess caregiver quality of life in relation to child otitis media. Assessment of the psychometric properties of this instrument is limited.

The Otitis Media-6 questionnaire: psychometric properties with emphasis on factor structure and interpretability.

Background: The Otitis Media-6 questionnaire (OM-6) is the most frequently used instrument to measure health related quality of life in children with otitis media. The main objectives of this study are 1) to translate and cross-culturally adapt the OM-6 into Danish, and 2) to assess important psychometric properties including structural validity and interpretability of the OM-6 in a Danish population of children suffering from otitis media.

Methods: The OM-6 was translated and cross-culturally adapted according to international guidelines.

Bronchoschopy should always be performed in children on suspicion of foreign body aspiration.

Introduction: Foreign body aspiration (FBA) can have a fatal outcome, and the diagnosis is challenging since symptoms and signs may vary. We therefore investigated whether it was possible to identify predictors indicating the presence of a foreign body.

Material And Methods: The medical records of children undergoing bronchoscopy at Odense University Hospital for suspected FBA in the period from 1977 to 2010 were reviewed and analyzed.

Surgical complications following cochlear implantation in adults based on a proposed reporting consensus.

Conclusion: The rate of severe complications was low and cochlear implantation is a relatively safe procedure. Standardization is crucial when reporting on cochlear implant complications to ensure comparability between studies. A consensus on the reporting of complications proposed by a Danish team of researchers was applied, evaluated and found beneficial.

Decreasing incidence rate for surgically treated middle ear cholesteatoma in Denmark 1977-2007.

Introduction: The objective was to estimate the annual incidence rate of surgically treated middle ear cholesteatoma (STMEC) in Denmark from 1977 to 2007, taking age, gender and secular trends into consideration.

Material And Methods: We used the Danish National Hospital Register to identify all registered cases of STMEC in Denmark between 1977 and 2007. Only the first registration of STEMC (STEMC1) was used for estimation of the annual incidence rate.

Validation of the cholesteatoma diagnosis in the Danish National Hospital Register.

Introduction: The aim was to evaluate the validity and the degree of completeness of the cholesteatoma diagnosis in the Danish National Hospital Register (DNHR).

Validity: A random sample of 286 patients with a cholesteatoma diagnosis who had been admitted to an ear-nose-throat department on Funen between 1977 and 2007 were selected from the DNHR for validation. The diagnosis was verified on the basis of surgical chart review.

[Otosyphilis].

We present a case in which a patient infected with human immunodeficiency virus (HIV) developed a sensorineural hearing loss and tinnitus due to inner-ear syphilis affection. The patient had normal otomicroscopy, tympanometry, ear, nose & throat examination, caloric test and intracranial magnetic resonance imagining. Relevant serological blood samples and lumbal puncture indicated syphilis in its secondary stage or the early latent phase.

[Results after stapedotomy in otosclerosis].

Introduction: The purpose of this study was to assess the results after primary otosclerosis surgery at Odense University Hospital.

Material And Methods: The study was based on information collected from a database and from patient records. A total of 154 primary stapedotomies (138 patients) were performed using small-fenester-technique in the period 1996-2005.

[Assessment of thyroplasty for vocal fold paralysis].

Introduction: Thyroplasty with silicone rubber implantation is a surgical procedure for treatment of patients with vocal fold paralysis. The aim of the present study was to evaluate the outcome of the operation and to monitor which of the analyses were the more beneficial.

Material And Methods: Twenty consecutive patients were enrolled in the study.

[Vocal fold palsy--investigation and follow-up].

Introduction: A new protocol for investigation of vocal fold palsy (VFP) was introduced in the ENT-department, Odense University Hospital on 1 January 2002. The protocol included ultrasonography (US) of the neck, x-ray of the chest and clinical examination at 3-month intervals for 1 year as well as MRI scanning of the brainstem, neck and mediastinum initially and after 6 months (or CT scanning under special circumstances). We have evaluated our protocol for investigation and in particular with regard to efficiency of diagnostic methods and the effect of long-term follow-up.

[Vocal fold palsy--etiology and outcome].

Introduction: The etiology of vocal fold palsy (VFP) is varied, and both Danish and foreign studies report variable frequencies of causes. We have evaluated etiologies of both unilateral (UVFP) and bilateral palsy (BVFP) and also analyzed the outcome of the palsies. As far as we know, our material is the largest published in Danish.

[Cochlear implantation in deaf adults: effect on quality of life].

Introduction: Our aim was to assess the effect of cochlear implant (CI) surgery on the mental quality of life in totally deaf adults using a generic type of questionnaire.

Materials And Methods: The survey comprised 40 adult CI users who answered a standard and a retrospective version of the Short Form 36 questionnaire (SF-36). In the questionnaires, specific questions focused on four dimensions of the mental quality of life: vitality, social functioning, and emotional and mental health.