Long-chain fatty acid uptake and oxidation in the perfused liver of Walker-256 tumour-bearing rats.

Aims/background: The effect of the Walker-256 tumour on uptake and oxidation of long-chain fatty acids was investigated in perfused livers of rats.

Methods: Isolated livers were perfused in a non-recirculating system. Fatty acid uptake, ketogenesis, oxygen uptake and 14CO2-production were measured as well as the activities of the acyl carnitine transferases I and II (CAT I and CAT II).