Publications by authors named "Christele Blanc-Bisson"
Impact of personalized diet and probiotic supplementation on inflammation, nutritional parameters and intestinal microbiota - The "RISTOMED project": Randomized controlled trial in healthy older people.
Clin Nutr
August 2015
Article Synopsis
- The study evaluated the effects of a personalized diet, with or without a probiotic supplement (VSL#3), on various health markers in 62 healthy older adults (ages 65-85) over an 8-week period.
- Participants who followed the diet alone saw reductions in inflammation markers (ESR), cholesterol, and glucose levels, while those who took VSL#3 experienced additional benefits like increased bifidobacteria and improved folate and vitamin B12 levels, especially if they had low-grade inflammation.
- Overall, the findings suggest that the combination of the personalized diet and VSL#3 may help improve gut health and lower homocysteine levels, indicating potential protective effects
Purpose: To determine factors associated with early functional decline during first-line chemotherapy in older patients.
Patients And Methods: Patients age ≥ 70 years receiving first-line chemotherapy for cancer were prospectively considered for inclusion across 12 centers in France. Functional decline was defined as a decrease of ≥ 0.
Purpose: Objective factors for making choices about the treatment of elderly patients with cancer are lacking. This investigation aimed to help physicians select appropriate treatments through the identification of factors that predict early death (< 6 months) after initiation of chemotherapy treatment.
Patients And Methods: Previously untreated patients greater than 70 years of age who were scheduled for first-line chemotherapy for various types of cancer were included.
Malnutrition is a common problem in cancer patients, associated with an increased risk of complications and a reduced response to treatment resulting to a poorer outcome. Both age and oncological disease can affect the state of nutrition in multiple ways. In elderly, malnutrition can be affected either directly by the tumour process (local effect, host response to the tumour .
View Article and Find Full Text PDFIn recent years, geriatricians and oncologists have worked together to evaluate elderly patients with cancer before and during treatment, to estimate the balance between the efficacy and safety of chemotherapy and to upgrade treatment in this population according to their comorbidity and physiological status. The clinical and biological factors of this population need to be assessed in multidisciplinary comprehensive geriatric assessment (CGA) in order to optimize treatment without inducing major adverse effects. We reviewed the nutritional aspects of this evaluation that highlight the impact of undernutrition on poor survival.
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