Inconclusive evidence that age predicts a prolonged or chronic course of acute rhinosinusitis in adults: a systematic review of the evidence base.

Objective: To review the evidence whether the risk for a prolonged or chronic course increases with age in adult patients with acute rhinosinusitis.

Data Sources: PubMed, EMBASE, and the Cochrane Library.

Review Methods: A comprehensive literature search was performed on March 24, 2013, and articles were screened and selected using predefined inclusion and exclusion criteria.