Publications by authors named "Christa Deprez"
Article Synopsis
- Ricin is a highly toxic substance from the castor bean plant, often resulting in severe poisoning through ingestion or injection, with injections being more deadly.
- The detection of ricin is challenging, so ricinine—a smaller compound found in the same beans—is used as a marker for ricin exposure, and a new LC-MS/MS method for quantifying ricinine levels in body fluids has been validated.
- A case study detailed a 26-year-old man who injected castor bean extract and experienced rapid health deterioration leading to his death, with significant ricinine levels found in his serum and urine, indicating lethal exposure.
Fentanyl, norfentanyl, alfentanil, sufentanil, remifentanil and 3-methylfentanyl are potent, short-acting, synthetic narcotic analgesics that are not revealed in standard opiate immunoassays. In this article, a fully validated analytical method for the determination of these fentanyl-type compounds in plasma and urine is presented, consisting of a liquid-liquid extraction followed by a LC-MS/MS analysis using electrospray ionisation in the positive ionisation mode. Fentanyl-d(5) and norfentanyl-d(5) were used as internal standards.
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