Modifications in the nitric acid oxidation of D-mannose: X-ray crystal structure of N,N'-dimethyl D-mannaramide.

Nitric acid oxidation of D-mannose was carried out under an oxygen atmosphere using a computer controlled reactor. The process represents a catalytic oxidation of D-mannose with oxygen as the terminal oxidant. The crude oxidation product was esterified with methanolic HCl and the esterified product directly converted to crystalline N,N'-dimethyl-D-mannaramide with methylamine.