The impact of regular bisoprolol on the response to salbutamol in asthma: A double-blind randomized placebo-controlled crossover trial.

Background And Objective: Non-selective beta-blockers impair the bronchodilator response to beta -agonists. Cardio-selective beta -blockers are less likely to cause this effect, yet they remain relatively contraindicated in asthma. We investigated whether the response to salbutamol is impaired during cardio-selective beta -blocker treatment in people with asthma.