[iOCT in clinical use : Correlation of intraoperative morphology and postoperative visual outcome in patients with full thickness macular hole].

Background: Due to intraoperative optical coherence tomography (iOCT), observation of retinal morphological changes during surgery has become possible.

Objective: To analyze the intraoperative morphology of full thickness macular holes (FTMH) and the correlation with the postoperative function, a retrospective, observational clinical study was performed analyzing 32 eyes of patients treated at the hospital of the technical university of Munich.

Material And Methods: Using iOCT in 32 eyes of 32 consecutive patients, the operative morphology was analyzed during surgery.

Inverted internal limiting membrane flap technique in eyes with large idiopathic full-thickness macular hole: long-term functional and morphological outcomes.

Purpose: To investigate morphological and functional outcomes of the inverted internal limiting membrane (I-ILM) flap technique in large (≥ 400 μm) idiopathic full-thickness macular holes (FTMH) over a follow-up period of 12 months.

Methods: In this retrospective study, 55 eyes of 54 consecutive patients were enrolled. Best-corrected visual acuity (BCVA) and spectral-domain optical coherence tomography (SD-OCT, Heidelberg, Spectralis) were performed preoperatively as well as 1, 3, 6, 9, and 12 months postoperatively.

Changes in the foveal microstructure after intravitreal bevacizumab application in patients with retinal vascular disease.

Purpose: To investigate changes in the area of the foveal avascular zone (FAZ) in patients with retinal vascular disease.

Patients And Methods: This retrospective, consecutive study examined 53 eyes of 53 patients with macular edema due to branch retinal vein occlusion in 25 patients (47.2%) and nonproliferative diabetic retinopathy in 28 patients (52.

First clinical results of epithelial laser in situ keratomileusis with a 1000 Hz excimer laser.

Purpose: To evaluate the safety, stability, and efficacy of the first clinical cases of epithelial laser in situ keratomileusis (epi-LASIK) performed using a 1000 Hz excimer laser system.

Setting: Klinikum Rechts der Isar, Munich, Germany.

Methods: The epi-LASIK procedure was performed using an EpiLift microkeratome and a WaveLight Concept System 1000 laser.

Critical flicker-fusion frequency in age-related macular degeneration.

Purpose: To assess the influence of age-related macular degeneration (AMD) on critical flicker-fusion frequency (CFF).

Methods: CFF was measured centrally for a red, green and blue target, and in 10 degrees excentricity with a red target. Twenty-eight patients with non-exsudative AMD, 12 patients with exsudative AMD and 45 age-matched healthy eyes were included.

Keratocyte density in the retroablation area after LASEK for the correction of myopia.

Purpose: During excimer laser photoablation keratocyte cell death is induced in the retroablation area. Afterwards this area is repopulated by keratocyte mitosis and migration from the adjacent stroma. The aim of this study was to investigate keratocyte density in the retroablation area and in the posterior stroma during the first year after LASEK for the correction of myopia.

Von Willebrand's disease type I as a cause for subvitreal, retinal and subretinal haemorrhages.

Background: Young patients with vitreous, retinal and subvitreal haemorrhages without neovascularisation or prior trauma are a diagnostic challenge for the physician. In this case report, a patient is presented who developed unilateral, spontaneous, subvitreal, retinal and subretinal haemorrhages and was diagnosed with von Willebrand's disease.

Case Report: A 33-year-old Caucasian woman presented at our clinic with unilateral subvitreal, retinal and subretinal haemorrhages.

Tear film function and corneal sensation in the early postoperative period after LASEK for the correction of myopia.

Purpose: Subepithelial nerves and stromal nerves of the cornea are damaged during LASEK surgery for the correction of myopia. This leads to a reduction in corneal sensation and to alterations of the tear film function in the early postoperative period. The aim of this study was to evaluate tear film function, corneal sensation and subjective symptoms of dry eye in the early postoperative period after LASEK for the correction of myopia.

Confocal microscopy and corneal sensitivity in a patient with corneal manifestations of Tangier disease.

Purpose: Tangier disease is an autosomal recessive disorder in which cholesterol-rich lipids are deposited at various tissues of the body including the cornea. In this case report, the corneal changes in a patient with Tangier disease are described.

Methods: A 72-year-old patient who was diagnosed with Tangier disease 25 years before received a complete eye examination including confocal microscopy and Cochet-Bonnet esthesiometry.

Corneal sensation after laser epithelial keratomileusis for the correction of myopia.

Background: Subepithelial nerve fibre bundles and stromal nerves are damaged during laser epithelial keratomileusis (LASEK). The aim of this study was to investigate the recovery of corneal sensation after LASEK for the correction of myopia.

Methods: Corneal sensation was evaluated in 40 eyes of 20 patients using a Cochet-Bonnet aesthesiometer before surgery and 3 days, 14 days, 1, 3 and 6 months after LASEK for the correction of mild to moderate myopia (range -2.