No Increased Risk of Major Adverse Cardiovascular Events following Nicotinamide Exposure.

Importance: Nicotinamide metabolites have recently been implicated in increased risk of major cardiovascular events (MACE). Supportive data about clinical risk of MACE for nicotinamide users is lacking.

Objective: To determine whether nicotinamide use results in an increase of MACE.

Genomic stratification beyond Ras/B-Raf in colorectal liver metastasis patients treated with hepatic arterial infusion.

Background: Resection of colorectal liver metastases (CLM) can cure disease, but many patients with extensive disease cannot be fully resected and others recur following surgery. Hepatic arterial infusion (HAI) chemotherapy can convert extensive liver disease to a resectable state or decrease recurrence risk, but response varies and no biomarkers currently exist to identify patients most likely to benefit.

Methods: We performed a retrospective cohort study of CLM patients receiving HAI chemotherapy whose tumors underwent MSK-IMPACT sequencing.

Long-term clinical outcome analysis of poly-methyl-methacrylate cranioplasty for large skull defects.

Purpose: The goal of secondary cranioplasty is permanent cerebral protection in an esthetically acceptable fashion. Reconstruction of cranial defects can be performed with several different materials. Alloplastic materials, such as preformed methyl-methacrylate (PMMA) cranioplasties, are an alternative frequently used at our institution.

Cuboid subluxation: a case study and review of the literature.

Cuboid subluxation involves displacement of the cuboid, resulting in pain and problems with push off during dancing or running. Its incidence varies with the population being studied, being apparently highest in ballet dancers. Most cuboid subluxations are plantar and medial, with rare dorsal subluxations.

Sports medicine practice economics part 3: billing, collecting, appeals, and related tasks.

Knowledge about proper coding in sports medicine will not benefit a physician or his or her practice if bills submitted to insurance companies are not regularly monitored and analyzed for trends. Physicians can help ensure successful collections by understanding the dynamics of reimbursement, enlisting the efforts of office colleagues, and facilitating patient involvement when appropriate. This is the third article in a three-part series about economics issues encountered in a sports medicine practice.

Sports medicine practice economics part 2: consultations, modifiers, and other codes.

Physicians face numerous challenges related to sports medicine practice economics, including coding and billing for consultations. Some of this difficulty stems from a lack of widespread recognition of sports medicine as a specialty. To further complicate matters, many insurance companies refuse to recognize dual credentials in both family medicine and sports medicine.

Sports medicine practice economics part 1: coding basics.

Proper understanding of coding, billing, and other practice economics issues in sports medicine is vital for practice success. Lack of accuracy and understanding in these areas may lead to problems that range from lost income to practice audits and potentially steep fines. A basic understanding of current procedural terminology (CPT), awareness of international classification of diseases (ICD-9) and healthcare common procedure coding system (HCPCS) codes, and the knowledge of how to apply them benefit sports medicine physicians.