Prevention of Cardiovascular Events in Patients With Chronic Kidney Disease.

Objective: To examine the evidence base for lifestyle and pharmacologic interventions to reduce the risk of cardiovascular events in patients with chronic kidney disease, with an emphasis on reporting available data in distinct subtypes.

Data Sources: A PubMed search (origin to February 2023) was conducted and references for selected studies were reviewed to identify additional articles. Search terms included chronic kidney disease, major adverse cardiovascular events, and heart failure hospitalization.

An estimate of meperidine usage in West Virginia hospitals.

Purpose: Meperidine (Demerol) is a synthetic opiate that has been utilized for decades. Nonetheless, its safety and efficacy profile relative to other opiates have led many to advocate against its use. We attempted to estimate current usage of meperidine by hospitals in West Virginia.

Methadone as an analgesic: a review of the risks and benefits.

While methadone has been available for over 50 years, its use in opiate dependence has overshadowed its use as an analgesic. Within the last 10-15 years, though, methadone has been increasingly used to manage neuoropathic pain and cancer pain, but its use is causing an alarming number of deaths in the U.S.