Publications by authors named "Chris M Callahan"
Article Synopsis
- * A meta-analysis was conducted using 38 articles on dementia and 31 on AD, with findings indicating a decrease in dementia incidence rates but stable rates for AD, particularly in Western countries.
- * The results suggest a decline in dementia cases among younger elderly populations, while non-Western countries have observed an increase in AD incidence for those aged 65-74, highlighting the need for updated public health strategies.
Introduction: Changes in glucose levels may represent a powerful metabolic indicator of dementia in African-Americans with diabetes. It is unclear whether these changes also occur in Caucasians.
Methods: A secondary data analysis using electronic medical records from 5228 African-Americans and Caucasians aged ≥65 years was carried out.
Introduction: High blood glucose levels may be responsible for the increased risk for dementia in diabetic patients.
Methods: A secondary data analysis merging electronic medical records (EMRs) with data collected from the Indianapolis-Ibadan Dementia project (IIDP). Of the enrolled 4105 African Americans, 3778 were identified in the EMR.
Article Synopsis
- Acetylcholinesterase inhibitors (ChEIs) like donepezil, rivastigmine, and galantamine are commonly used to treat mild to moderate Alzheimer's disease, but adherence to these medications is not well studied.
- This clinical trial aims to assess adherence rates and reasons for nonadherence among older adults in Indianapolis, using caregiver interviews and electronic health records to gather data over 18 weeks.
- The study will also explore factors like pharmacogenomics that may affect how well patients tolerate and adhere to ChEIs in a real-world setting involving diverse memory care practices.