Publications by authors named "Chris Luyten"
Article Synopsis
- The study investigates antioxidant defense levels in patients with acute exacerbations of COPD compared to stable patients, analyzing the extent and timing of these defenses.
- Twelve patients were monitored at various times after admission, focusing on both endogenous and exogenous antioxidants, including glutathione peroxidase and alpha-tocopherol.
- Results showed increased antioxidant activity over 48 hours, but the rise was insufficient to prevent depletion of non-enzymatic antioxidants like alpha-tocopherol.
Objective: Cardiac surgery may lead to severe oxidative stress due to formation of oxidation products generated during ischemia and reperfusion. We investigated to which extent oxidative stress influences a number of endogenous antioxidants and markers of cellular activation.
Methods: At six time points blood was withdrawn from patients undergoing coronary artery bypass grafting, using the on-pump procedure.