Publications by authors named "Chris Kimble"

Objectives: The evaluation of telemedicine from the patient's point of view has focused on the patient pathway and patient satisfaction. However, research in this field does not provide us with the means to assess a patient's perception of the procedure if their reasoning ability is impaired. In this study, we use direct observation of a patient's behavior and mood to assess their perception of an oral teleconsultation procedure.

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Article Synopsis
  • Scientists studied how deep brain stimulation (DBS) helps people with Parkinson's disease by using pigs, since their brains are more similar to humans than mice.
  • They found that when they stimulated the brain in pigs, it caused a release of dopamine, a chemical that helps control movement, and the amount released depended on how strong and how fast they stimulated.
  • This research shows that using large animals can give better insights into how DBS works, and it suggests that the stimulation might activate certain brain cells that release dopamine, which helps improve movement in Parkinson's patients.
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Deep Brain Stimulation (DBS) provides therapeutic benefit for several neuropathologies including Parkinson's disease (PD), epilepsy, chronic pain, and depression. Despite well established clinical efficacy, the mechanism(s) of DBS remains poorly understood. In this review we begin by summarizing the current understanding of the DBS mechanism.

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