A Computational Approach to Modeling Excitation Energy Transfer and Quenching in Light-Harvesting Complexes.

Light-harvesting complexes (LHCs) play a critical role in modulating energy flux within photosynthetic organisms in response to fluctuating light. Under high light conditions, they activate quenching mechanisms to mitigate photodamage. Despite their importance, the molecular mechanisms underlying these photoprotective processes remain incomplete.

On assessing the carbon capture performance of graphynes with particle swarm optimization.

Tackling climate change is one of the greatest challenges of current times and therefore the development of efficient technologies to limit anthropogenic emissions is of utmost urgency. Recent research towards this goal has alluded to the use of carbon-based solid sorbents for carbon capture. Graphynes (GYs), an interesting class of porous carbon membranes, have recently proven their potential as excellent membranes for gas adsorption and separation.

Revolutionizing Cardiac Care: A Comprehensive Narrative Review of Cardiac Rehabilitation and the Evolution of Cardiovascular Medicine.

Cardiovascular disease (CVD) stands as a global health crisis, with its complex web of conditions, including coronary artery disease, heart failure, hypertension, and stroke, continuing to exact a heavy toll on individuals and healthcare systems worldwide. Despite substantial advances in medical technology and pharmaceutical interventions, CVD remains a formidable adversary, necessitating innovative prevention, management, and rehabilitation approaches. In tracing the historical trajectory of CVD, the narrative reveals the antiquated practices of early 20th-century medicine, marked by extended bed rest as the primary modality for heart-related conditions.

The Bidirectional Link Between Diabetes and Kidney Disease: Mechanisms and Management.

The complex and mutually influential connection between diabetes mellitus and chronic kidney disease (CKD) is a significant focal point in the current healthcare landscape. Diabetes, a medical condition characterized by elevated blood glucose levels resulting from impaired insulin action or secretion, has become a significant global epidemic. It poses considerable challenges to healthcare systems and affects millions of individuals worldwide.

Global Optimization of Dinitrogen Clusters Bound to Monolayer and Bilayer Graphene: A Swarm Intelligence Approach.

Locating the global minimum of a potential energy surface is an arduous task. The complexity of the potential energy surface increases as the number of degrees of freedom of the system increases. The highly rugged nature of the potential energy surface makes the minimization of the total energy of the molecular clusters a difficult optimization problem.

Collaborative case-based learning with programmatic team-based assessment: a novel methodology for developing advanced skills in early-years medical students.

Background: Imperial College London launched a new, spiral undergraduate medical curriculum in September 2019. Clinical & Scientific Integrative cases (CSI) is an innovative, flagship module, which uses pioneering methodology to provide early-years learning that [1] is patient-centred, [2] integrates clinical and scientific curriculum content, [3] develops advanced team-work skills and [4] provides engaging, student-driven learning. These aims are designed to produce medical graduates equipped to excel in a modern healthcare environment.

An anisotropic dressed pairwise potential model for the adsorption of noble gases on boron nitride sheets.

Development of empirical potentials with accurate parameterization is indispensable while modeling large-scale systems. Herein, we report accurate parameterization of an anisotropic dressed pairwise potential model (PPM) for probing the adsorption of noble gases, He, Ne, Ar and Kr on boron nitride sheets. For the noble gas binding on BNH, we carried out a least-squares fit analysis of the dispersion and dispersionless contributions of the interaction potential separately.

A swarm intelligence modeling approach reveals noble gas cluster configurations confined within carbon nanotubes.

Confinement of atoms and molecules brings forth fascinating properties to chemical systems that are otherwise not known in the bulk. Carbon nanotubes (CNTs) and fullerenes are excellent hosts for probing the confinement effects. Herein, we explore the potential energy surfaces of large noble gas clusters, Ngn (Ng = He, Ne and Ar; n = 10, 20, 30, 40, and 50), in the confines of CNTs of various lengths.

Quantum Transmission of He Isotopes through Crown Ether-Embedded Graphene Nanomeshes: An Eckart Potential Approach.

The remarkable performance of carbon membranes for the selective passage of various species has led to extensive research in designing smart membranes. The mechanical stability of graphene in conjunction with the excellent host-guest chemistry of crown ethers makes the recently synthesized family of crown ether-embedded graphene nanomeshes promising candidates for sieving applications. Inspired by the excellent control over pore architectures offered by such nanomeshes, we investigate the abilities of crown ether-embedded graphene nanomeshes for noble gas separation by the size-sieving mechanism and for He isotope separation by the quantum sieving mechanism.

From workforce intelligence to workforce development: advancing the Eastern Mediterranean pharmaceutical workforce for better health outcomes.

Background: The pharmaceutical workforce in the World Health Organization (WHO) Eastern Mediterranean Region plays a key role in improving health outcomes through responsible use of drugs and optimizing effective choice and use. Investment in this workforce's development and planning is fundamental to achieving universal health coverage.

Aims: To provide an overview of the pharmacy workforce capacity trends in the Region and emphasize the importance of workforce intelligence for strategic development.

Graphynes: indispensable nanoporous architectures in carbon flatland.

Theoretical design and experimental realization of novel nanoporous architectures in carbon membranes has been a success story in recent times. Research on graphynes, an interesting class of materials in carbon flatland, has contributed immensely to this success story. Graphyne frameworks possessing sp and sp hybridized carbon atoms offer a variety of uniformly distributed nanoporous architectures for applications ranging from water desalination, gas separation, and energy storage to catalysis.

Selective Permeation through One-Atom-Thick Nanoporous Carbon Membranes: Theory Reveals Excellent Design Strategies!

Research on the permeation of various species through one-atom-thick nanoporous carbon membranes has gained an unprecedented importance in the past decade, thanks to the development of numerous theoretical design strategies for a plethora of applications ranging from gas separation, water desalination, isotope separation, and chiral separation, to DNA sequencing. Although some of the recent experiments have demonstrated successful performance of such carbon membranes in sieving, many of the suggested applications are yet to be realized in experiments. This review aims to draw the attention of the theoretical as well as the experimental researchers working on two-dimensional carbon materials toward the recent theoretical developments probing the permeation of various species such as atoms, ions, small molecules, and biopolymers like DNA through carbon frameworks like graphynes, graphdiyne, graphenylenes, and various forms of nanoporous graphene, including graphene crown ethers.

Single-incision repair of acute distal biceps ruptures by use of suture anchors.

The purpose of this study is to report the results of a single limited-incision technique for repair of acute distal biceps ruptures by use of suture anchors. Sixty consecutive patients underwent distal biceps repair after an acute rupture between January 1997 and January 2001 by use of a limited antecubital incision and suture anchors. Fifty-three patients could be evaluated at a mean follow-up of 38.

Helping people assess the health risks from lifestyle choices: comparing a computer decision aid with customized printed alternative.

Decisions about lifestyle play a key role in influencing health. Illnesses such as heart disease result from combinations of factors, making it hard for people to evaluate alternatives (e.g.