Detecting chronic kidney disease in older people; what are the implications?

Background: national policy is focused on early identification, referral and management of chronic kidney disease (CKD) to prevent both progression to endstage renal failure and cardiovascular disease. However, the significance of identifying CKD in older people is unclear.

Objective: to determine the frequency of CKD in older people using estimated glomerular filtration rate (eGFR), and its associations with morbidity and functional measures.

Prevalence of cognitive impairment: results from the MRC trial of assessment and management of older people in the community.

Background: cognitive impairment is an important part of the diagnostic criteria for dementia. The Mini-Mental State Examination (MMSE) is recommended to test for cognitive impairment and to monitor medication response.

Objectives: we examined the prevalence of cognitive impairment in the UK and assessed associations with cognitive impairment.

Local area deprivation and urban-rural differences in anxiety and depression among people older than 75 years in Britain.

Objectives: We sought to determine the association of depression and anxiety with "area deprivation" (neighborhood socioeconomic deprivation) and population density among people older than 75 years in Britain.

Methods: Postal codes were used to link census area information to individual data on depression and anxiety in 13349 people aged 75 years and older taking part in a trial of health screening.

Results: Living in the most socioeconomically deprived areas was associated with depression (OR=1.