Publications by authors named "Chris Hebert Jesus Franco"
Article Synopsis
- A series of transition metal coordination polymers containing zinc and copper were synthesized using fluconazole and various metal salts under mild conditions, resulting in six new compounds.
- The structures of these compounds were confirmed through various analytical techniques, including single-crystal X-ray diffraction for four of the compounds.
- The compounds showed significant antichagasic activity against Trypanosoma cruzi, with one compound (2) being particularly effective, suggesting that these coordination polymers could be better therapeutic options than the free azole drug for Chagas disease.
A series of new metal complexes, [Zn(KTZ)(Ac)]·HO (1) [Zn(KTZ)Cl]·0.4CHOH (2), [Zn(KTZ)(HO)(NO)](NO) (3), [Cu(KTZ)(Ac)]·HO (4) [Cu(KTZ)Cl]·3.2HO (5), [Cu(KTZ)(HO)(NO)](NO)·HO (6), were synthesized by a reaction of ketoconazole (KTZ) with their respective zinc or copper salts under mild conditions.
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