Publications by authors named "Chris Gottschalk"

Wine grape ( L.) is the most widely cultivated fruit crop in the world. However, the climactic characteristics in some growing regions are suboptimal for grape production, including short season length and excess precipitation.

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Many apple cultivars are subject to biennial fluctuations in flowering and fruiting. It is believed that this phenomenon is caused by a repressive effect of developing fruit on the initiation of flowers in the apex of proximal bourse shoots. However, the genetic pathways of floral initiation are incompletely described in apple, and the biological nature of floral repression by fruit is currently unknown.

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Article Synopsis
  • The first whole genome sequence (WGS) for apple was published in 2010, serving as a crucial reference for gene mapping and discovery, followed by a high-quality update in 2017.
  • These genomic advancements have significantly enhanced our understanding of apple biology, trait inheritance, and improved techniques for crop enhancement and breeding.
  • The review discusses practical breakthroughs, ongoing challenges, and future recommendations for upgrading the apple genome data to further advance genomics research in apple cultivation.
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Purpose: Statistical parametric mapping (SPM) is an image-analysis tool that assesses the statistical significance of cerebral blood flow (CBF) changes on a voxel-by-voxel basis, thereby removing the subjectivity inherent in conventional region-of-interest (ROI) analysis. Our platform of single-photon emission computed tomography (SPECT) ictal-interictal difference imaging in clinical epilepsy has been validated for localizing seizure onset. We extend the tools of SPM by further applying statistical measures for the significance of perfusion changes in individual patients to localize epileptogenic foci in patients with defined temporal lobe epilepsy by using paired scans in this preliminary study.

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