Publications by authors named "Chris Fenner"
Article Synopsis
- Venous leg ulcers (VLUs) are challenging to treat, with a significant percentage not healing even after months of standard compression therapy, making the exploration of additional treatments like aspirin important.
- A pilot trial involving random assignments of chronic VLU patients to receive either 300 mg of daily aspirin or a placebo aimed to assess the efficacy, safety, and recruitment feasibility for future studies.
- The trial recruited 27 participants, but faced recruitment challenges, and ultimately found no significant difference in healing times between the aspirin and placebo groups, suggesting aspirin may not be effective for VLU treatment.
Background: Venous leg ulcers (VLUs) are the most common cause of leg ulceration, affecting 1 in 100 adults. VLUs may take many months to heal (25% fail to heal). Estimated prevalence is between 1% and 3% of the elderly population.
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