Publications by authors named "Chris Almquist"
Article Synopsis
- Diabetes mellitus causes significant, irreversible damage to peripheral nerves, impairing their ability to regenerate, resulting in conditions like carpal tunnel syndrome and diffuse polyneuropathy.
- Researchers discovered that increased levels of PTEN, a protein, in diabetic peripheral neurons hinder axon regrowth.
- By reducing PTEN through a unique RNA delivery method in a chronic diabetic model, significant improvements in nerve regeneration and recovery of sensory and motor functions were observed, suggesting a potential new therapy for diabetic neuropathy.
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