Down-regulation of PRKCB1 expression in Han Chinese patients with subsyndromal symptomatic depression.

Background: Subsyndromal symptomatic depression (SSD) is a common disease with significant social dysfunction. However, SSD is still not well understood and the pathophysiology of it remains unclear.

Methods: We classified 48 candidate genes for SSD according to our previous study into clusters and pathways using DAVID Bioinformatics Functional Annotation Tool.