Publications by authors named "Choukairi Mohamed"
Article Synopsis
- A new Sonogel-Carbon (SNGC) electrode, enhanced with the amino acid l-leucine, has been created for detecting homovanillic acid (HVA) effectively.
- Electrochemical techniques like cyclic voltammetry and impedance spectroscopy confirmed the performance of the SNGC-Leu electrode, which demonstrated a linear detection range for HVA from 0.5 μM to 50 μM and a detection limit of 0.4 μM.
- The SNGC-Leu sensor showed high accuracy in real applications, successfully measuring HVA in human urine and synthetic cerebrospinal fluid with impressive recovery rates.
This work presents a significant investigation involving both electrochemical experiment and quantum chemical simulation approaches. The objective was to characterize the electrochemical detection of dopamine (DA). The detection was carried out using a modified carbon paste electrode (CPE) incorporating bentonite (Bent) and l-cysteine (CySH) (named as CySH/Bent/CPE).
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- This study focuses on creating an effective electrochemical electrode by adding potassium montmorillonite (MMT) clay to a carbon matrix, aimed at accurately detecting paracetamol (PAR) in pharmaceuticals.
- The electrode's performance is characterized using methods like cyclic voltammetry and differential pulse voltammetry, showing a responsive detection range for PAR and a low limit of detection (0.46 μM) with around 94% recovery.
- The research utilizes density functional theory (DFT) and Monte Carlo simulations to explore PAR's interactions on the electrode surface, confirming strong correlations between theoretical predictions and experimental findings, leading to a sensor with rapid response, high sensitivity, and durability.
Paracetamol (PCT), or acetaminophen, is an important drug used worldwide for various clinical purposes. However, the excessive or indiscriminate use of PCT can provoke liver and kidney dysfunction; hence, it is essential to determine the amount of this target in biological samples. In this work, we develop a quick, simple, and sensitive voltammetric method using chemically modified electrodes to determine PCT in complex matrices, including human serum and commercial solid formulations.
View Article and Find Full Text PDFA novel modification of a paste carbon electrode by Bentonite (Bent) and l-Cysteine (l-Cyst) was carried out for uric acid (UA) and ascorbic acid (AA) detection and quantification. Morphological and compositional characterization of the electrode surface were carried out using electrochemical impedance spectroscopy (EIS), scanning electron microscopy (SEM) and energy dispersive X-ray spectroscopic analysis (EDS). Cyclic voltammetry (CV) and square wave voltammetry (SWV) techniques were used to analyze UA and AA.
View Article and Find Full Text PDFA novel l-leucine modified Sol-Gel-Carbon electrode for simultaneous electrochemical detection of homovanillic acid, dopamine and uric acid in neuroblastoma diagnosis.
Mater Sci Eng C Mater Biol Appl
February 2017
Neuroblastoma is a pediatric neuroblastic tumor arising in the sympathetic nervous crest cells. A high grade of Neuroblastoma is characterized by a high urinary excretion of homovanillic acid and dopamine. In this work l-leucine modified Sol-Gel-Carbon electrode was used for a sensitive voltammetric determination of homovanillic acid and dopamine in urine.
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