In vitro antimicrobial and cytotoxic activities of ferrocene derivative compounds.

The aim of the present study was to investigate the biocidal activity of four new ferrocene derivative based coordination complexes, [1,2,3-trithia-/3/-ferrocenophane, C1]; [disodium-1,1'-ferrocenedithiolate, C2]; [1,1'-(ferrocene-1,1'-diyl)-diethanol, C3]; [ferrocenyl(ethyl-phenyl)-methanol, C4]; against microbes (bacteria and fungi) and brine shrimp (Artemia salina Lech.) nauplii. C2 showed modest antibacterial activity at the concentration of 200 microg disc(-1) and gave its Minimum Inhibitory Concentration values at 32-64 microg mL(-1) against the tested bacteria.

Adducts of 1,4,8,11-tetraazacyclotetradecane with carboxylic acids: hydrogen-bonded supramolecular structures in two or three dimensions.

Four solvated salt-type adducts derived from cyclam (1,4,8,11-tetraazacyclotetradecane) and carboxylic acids have been structurally characterized. In the salt derived from adamantane-1-carboxylic acid, 4,11-diaza-1,8-diazoniacyclotetradecane bis(adamantane-1-carboxylate) tetrahydrate, (1) (monoclinic, P2(1)/c, Z' = 0.5), where the cation lies across a centre of inversion, the anions and the water molecules form chains of edge-fused R(4)(2)(8) and R(6)(6)(16) rings, which are linked into sheets by the cations.

Adducts of hexamethylenetetramine with ferrocenecarboxylic acid and ferrocene-1,1'-dicarboxylic acid: multiple disorder in space groups Fmm2 and Cmcm.

Hexamethylenetetramine, C(6)H(12)N(4), and ferrocenecarboxylic acid, C(11)H(10)FeO(2), form a 1:2 adduct, (I), which is a salt, viz. hexamethylenetetraminium(2+) bis(ferrocenecarboxylate), (C(6)H(14)N(4))[Fe(C(5)H(5))(C(6)H(4)O(2))](2). The dication in (I) is disordered with two orientations at a site of mm2 symmetry in space group Fmm2, while the anion lies across a mirror plane with its unsubstituted cyclopentadienyl ring disordered over two sets of sites.

(1R,3S)-Camphoric acid as a building block in supramolecular chemistry: adducts with organic polyamines.

(1R,3S)-Camphoric acid [(1R,3S)-1,2,2,-trimethylcyclopentane-1,3-dicarboxylic acid, C(10)H(16)O(4)] forms adducts with a range of amines in which the acid component may be the neutral molecule, the mono-anion (C(10)H(15)O(4))(-) or the di-anion (C(10)H(14)O(4))(2-). The structures generated by the hard hydrogen bonds take the form of chains in the 1:1 adducts (II) and (III) formed with 4,4'-bipyridyl and 1,2-bis(4-pyridyl)ethane. There are single sheets in the hydrated 1:1 adduct (IV) formed with 1,4-diazabicyclo[2.

Phosphonoacetic acid as a building block in supramolecular chemistry: salts with organic polyamines.

Phosphonoacetic acid, (HO)(2)P(O)CH(2)COOH, forms adducts with a range of amines. The acid component in these adducts may be the neutral molecule C(2)H(5)O(5)P, the mono-anion (C(2)H(4)O(5)P)(-) or the di-anion (C(2)H(3)O(5)P)(2-). The substructure formed by the acid component takes the form of simple chains in compounds (1)-(3), which are the 1:1 adducts formed with 1,4-diazabicyclo[2.

Ferrocene-1,1'-dicarboxylic acid as a building block in supramolecular chemistry: supramolecular structures in one, two and three dimensions.

The supramolecular structures have been determined for nine adducts formed between organic diamines and ferrocene-1,1'-dicarboxylic acid. In the salt-like 1:1 adduct (1) formed with methylamine, the supramolecular structure is one-dimensional, whereas in the 1:1 adducts formed with 1,4-diazabicyclo[2.2.

N,N'-Dithiobisphthalimide-1,4-dioxan (1/0.6): a C2/c solvate with disordered solvent molecules localized in channels.

N,N'-Dithiobisphthalimide crystallizes from 1,4-dioxan solution as a solvate, 3C(16)H(8)N(2)O(4)S(2) x 1.8C(4)H(8)O(2), having space group C2/c. Four of the 12 C(16)H(8)N(2)O(4)S(2) molecules in the unit cell lie on twofold rotation axes, while the other eight lie in general positions.

Adducts of 1,1,1-tris(4-hydroxyphenyl)ethane with diamines: three-dimensional hydrogen-bonded frameworks formed with 1,6-diaminohexane and 2,2'-bipyridyl.

The adduct 1,6-diaminohexane-1,1,1-tris(4-hydroxyphenyl)ethane (1/2) is a salt (hexane-1,6-diyldiammonium-4-[1,1-bis(4-hydroxyphenyl)ethyl]phenolate (1/2)), C(6)H(18)N(2)2+ x 2C(20)H(17)O(3)(-), in which the cation lies across a centre of inversion in space group P-1. The anions are linked by two short O-H* * *O hydrogen bonds [H* * *O 1.74 and 1.

Polymorphs and pseudopolymorphs of N,N'-dithiobisphthalimide.

N,N'-Dithiobisphthalimide, C(16)H(8)N(2)O(4)S(2) (I), forms a wide range of polymorphs and solvates (pseudopolymorphs). When (I) is crystallized from methanol it yields a solvent-free polymorph (4), in Pna2(1) with Z' = 1, in which the molecules are linked into chains by a single C-H.O hydrogen bond: crystallization from either acetonitrile or dimethylformamide produces a monoclinic polymorph (5), in P2(1)/c with Z' = 2, also solvent-free, in which the molecules are linked into molecular ladders.

[Ni(cyclam)(OCOR)2], a finite molecular complex: hydrogen-bonded supramolecular aggregation in one, two and three dimensions, and coordination polymers in one and two dimensions.

In the complexes [Ni(cyclam)(OCOR)2] (cyclam = 1,4,8,11-tetraazacyclotetradecane), where (RCOO)- is 2-naphthoate [bis-(2-naphthoato)-1,4,8,11-tetraazacyclotetradecanenickel(II), (I), monoclinic P2(1)/c, Z' = 0.5], 3,5-dinitrobenzoate [bis-(3,5-dinitrobenzoato)-1,4,8,11-tetraazacyclotetradecanenickel(II), (II), triclinic P1, Z' = 0.5], 4-nitrobenzoate [bis-(4-nitrobenzoato)-1,4,8,11-tetraazacyclotetradecanenickel(II), (III), monoclinic P2(1)/n, Z' = 0.

Phthalimide at 120 K: perforated molecular ribbons containing three different ring motifs.

Molecules of phthalimide [1H-isoindole-1,3(2H)-dione], C8H5NO2, are linked by N-H...

Adducts of 1,1,1-tris(4-hydroxyphenyl)ethane with 1,2-bis(4-pyridyl)ethane and 1,2-bis(4-pyridyl)ethene: continuously interwoven structures in three dimensions.

In the adduct 1,2-bis(4-pyridyl)ethane-1,1,1-tris(4-hydroxyphenyl)ethane (1/2), C12H12)2*2C20H18O3, the bipyridyl component lies across an inversion centre in P-1. The tris-phenol molecules [systematic name: 4,4',4"-(ethane-1,1,1-triyl)triphenol] are linked by O-H..

Hydrogen-bonded adducts of ferrocene-1,1'-diylbis(diphenylmethanol): a finite cyclic 1:1 adduct with 2,2'-dipyridylamine.

In ferrocene-1,1'-diylbis(diphenylmethanol)-2,2'-dipyridylamine (1/1), [Fe(C18H15O)2]*C10H9N3, (I), there is an intramolecular O-H...

Hydrogen-bonded adducts of ferrocene-1,1'-diylbis(diphenylmethanol): monomeric and polymeric adducts with 1,2-bis(4-pyridyl)ethene and 1,6-diaminohexane.

In the adduct ferrocene-1,1'-diylbis(diphenylmethanol)-1,2-bis(4-pyridyl)ethene (1/1), [Fe(C18H15O)2]*C12H10N2, there is an intramolecular O-H...