Congenital dyserythropoietic anaemias: splenectomy as a mode of therapy.

3 cases of congenital dyserythropoietic anaemia (type I, case 3; type III, cases 1 and 2) are reported with a follow-up of 8-10 years. Conventional therapy with vitamins, steroids and/or anabolic hormones was ineffective. Regular blood transfusions were required to maintain the haemoglobin levels around 8 g/dl.

Nutritional anaemia in children.

This article discusses the larger group of nutritional anemias in childhood. The etiology, physiological changes, prevention and management of these entities are presented in an appropriate, concise manner, suitable for the practitioner. Special emphasis has been given to pathophysiological changes leading to haematological problems.

Chloroquine induced haemolysis and acute renal failure in subjects with G-6-PD deficiency.

Three male children with G-6-PD deficiency developed intravascular haemolysis leading to acute renal insufficiency following the administration of chloroquine. In two cases chloroquine seemed to be the only offending agent. One child required peritoneal dialysis.