Publications by authors named "Chou C"

The physicochemical characteristics of noodles prepared using Taiwan Oolong banana were evaluated. To prepare noodles, wheat flour was partially substituted with Oolong banana flour (OBF) in different levels (0, 2.5, 0.

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Background: Mast cells are implicated in the pathogenesis and severity of asthma in children and adults. The release of proinflammatory mediators and cytokines from activated mast cells (MC) is associated with Type 2 (T2) cell-skewed inflammation.

Methods: We obtained the airway tissues of Balb/c mice with or without intra-tracheal diesel exhaust particles (DEP) instillation to measure the extent of tryptase MCs infiltration and interleukin (IL)-33 expression.

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Purpose: Intraoperative topical vancomycin has been widely used in several surgical fields to prevent wound infection. However, there have been limited studies on the systemic exposure of topical vancomycin. The aim of this study was to investigate systemic exposure after topical vancomycin over the sternal edge in cardiac surgical patients.

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Oxide superlattices reveal a rich array of emergent properties derived from the composition modulation and the resulting lattice distortion, charge transfer, and symmetry reduction that occur at the interfaces between the layers. The great majority of studies have focused on perovskite oxide superlattices, revealing, for example, the appearance of an interfacial 2D electron gas, magnetic moment, or improper ferroelectric polarization that is not present in the parent phases. Garnets possess greater structural complexity than perovskites: the cubic garnet unit cell contains 160 atoms with the cations distributed between three different coordination sites, and garnets exhibit a wide range of useful properties, including ferrimagnetism and ion transport.

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Background/purpose: Telemedicine is an innovative medical care system that facilitates visual communication between patients and healthcare workers (HCWs), mainly in a community-based setting. We investigated the clinical effectiveness of in-patient telemedicine care for patients in quarantine for the Coronavirus disease 2019 (COVID-19).

Methods: We conducted a prospective study to include patients with mild-to-moderate severity of COVID-19 and their primary-care HCWs.

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Article Synopsis
  • This study investigates the use of serum inflammatory markers as prognostic indicators for survival in patients with metastatic urothelial carcinoma (mUC) receiving immune checkpoint inhibitors (ICIs).
  • Data from two medical centers in Taiwan were analyzed, focusing on markers like neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR), to assess their impact on overall and progression-free survival.
  • The findings suggest that specific inflammatory markers, along with other clinical factors, can effectively predict patient outcomes, emphasizing the need for reliable prognostic tools in mUC treatment.
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Background: Nemonoxacin is a novel non-fluorinated quinolone antibiotic for the treatment of community-acquired pneumonia. To investigate the pharmacokinetics (PK) of nemonoxacin, a simple and sensitive high-performance liquid chromatography assay (HPLC) was needed.

Methods: An HPLC method with fluorescence (FL) detection was developed for the quantification of nemonoxacin in plasma and bile.

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Objectives: Healthcare providers with low patient experience scores may provide suboptimal care and experience burnout. Communication skills training (CST) can be effective, but remedial programs may be poorly received. We aimed to create a program to support advanced practice providers (APPs) with lowest patient experience ratings.

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Unlabelled: BluePoint MoldID can identify 43 fungal species through nucleic acid array hybridization and matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) can identify 247 filamentous fungi through mass spectrometry. First, 43 standard isolates from the Bioresource Collection and Research Center, Taiwan, and the College of American Pathologists and 41 clinical species isolates confirmed by rDNA-ITS sequencing were analyzed using BluePoint MoldID and Bruker MALDI-TOF MS. BluePoint MoldID accurately identified 79% (34/43) of the standard isolates to the species level but failed to recognize nine isolates absent from its database; additionally, 87.

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Probiotics, known for their health benefits as living microorganisms, hold significant importance across various fields, including agriculture, aquaculture, nutraceuticals, and pharmaceuticals. Optimal delivery and storage of probiotic cells are essential to maximize their effectiveness. Biopolymers, derived from living sources, plants, animals, and microbes, offer a natural solution to enhance probiotic capabilities and they possess distinctive qualities such as stability, flexibility, biocompatibility, sustainability, biodegradability, and antibacterial properties, making them ideal for probiotic applications.

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Black carbon, or soot, significantly contributes to atmospheric light absorption due to its low single scattering albedo (SSA). This study investigates the impact of soot's hygroscopic restructuring on satellite remote sensing, focusing on radiative forcing, top-of-atmosphere (TOA) reflectance, and aerosol optical depth (AOD) retrievals. We characterized soot aging using relative humidity (RH) growth factor functions and modeled fresh and aging soot aggregates using a cluster-cluster aggregation algorithm.

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Objective: The genetic causes of a significant number of patients with cerebellar ataxia remain unsolved. Variations in the ITM2B gene, typically linked to dominantly inherited dementia, can sometimes present with cerebellar ataxia as an early symptom. This study aims to investigate the role of ITM2B variations in a Taiwanese cohort with unsolved cerebellar ataxia.

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Objective: To develop and validate a patient-reported outcome measure (PROM) to evaluate the quality of life (QoL) among patients with obstructive sleep apnea (OSA).

Study Design: A prospective cohort study.

Settings: Tertiary referral center.

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Article Synopsis
  • - The study investigates how aeration tanks in wastewater treatment plants (WWTPs) release airborne antibiotic resistance genes (ARGs) and antibiotic-resistant bacteria (ARB), particularly noting the impact of bubble bursts at the air-liquid interface.
  • - Researchers found that the ARG levels in particulate matter (PM) were significantly higher than in wastewater, suggesting that ARGs can be transmitted through the air, with certain bacteria like Mycobacterium and Gordonia being key contributors to this phenomenon.
  • - The analysis indicates that these airborne ARGs are more resilient due to stress response genes, leading to heightened risks of exposure and potential health impacts from ARG-laden PM in the atmosphere.
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Magnetic sensing beyond the linear regime could broaden the frequency range of detectable magnetic fields, which is crucial to various microwave and quantum applications. Recently, nonlinear interactions in diamond nitrogen-vacancy (NV) centers are proposed to realize magnetic sensing across arbitrary frequencies. In this work, we enhanced these capabilities by exploiting the nonlinear spin dynamics in hybrid systems of NV centers and ferri- or ferromagnetic (FM) thin films.

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  • New technologies have greatly advanced animal behavior studies, but similar approaches in human psychiatry are lacking.
  • This study used machine learning to analyze spontaneous behaviors in individuals with bipolar disorder (BD) and non-BD participants in an open-field setting.
  • The research introduced innovative measures to quantify behavioral dynamics and variability in BD, providing a better understanding of cognitive patterns and improving predictions of BD compared to traditional methods.
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  • Higher brain functions rely on how experiences shape information representation, potentially organized through attractor dynamics or changes in neural manifolds.
  • Research on zebrafish's olfactory responses showed that instead of attractor dynamics, training improved the differentiation of neural representations for relevant odors, in line with autoassociative network models.
  • The geometry of these neural manifolds was crucial for classifying sensory information and predicting odor discrimination, indicating that areas like pDp might encode information in a way that supports both sensory and meaningful learning.
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Subjective cognitive decline (SCD) may serve as an early indicator of Alzheimer's disease (AD). This study investigates regional cerebral blood flow (rCBF) alterations in individuals with SCD using single photon emission computed tomography (SPECT). To characterize rCBF patterns in SCD patients compared to healthy controls and examine the relationship between rCBF and cognitive function.

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Background: Weight control behaviors are commonly observed among adolescents and emerging adults. However, the high prevalence of overweight and obesity in both these age groups remains an imperative health concern. Adolescents and emerging adults represent the most vulnerable groups facing the health burden of obesity.

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Introduction: Neoadjuvant concurrent chemoradiotherapy (CCRT) is routinely used before surgery in patients with locally advanced rectal cancer to reduce tumor size and decrease the risk of local recurrence. However, the disease-specific survival has not improved in most cases due to distant metastases. In selected individuals exhibiting a clinical complete response, non-operative management may be allowed; however, those who presented no or little response tend to have an inferior prognosis.

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  • Lung cancer is a major cause of cancer deaths globally, with Black/African American (B/AA) populations facing the highest rates of lung adenocarcinoma incidence and mortality in the U.S.
  • This study analyzes gene expression patterns linked to lung adenocarcinoma in B/AA patients compared to white patients, using RNA sequencing data to identify genes and pathways affecting overall survival.
  • Findings revealed distinct OS-associated genes in B/AA patients, especially enriched in immune-related pathways, leading to the development of predictive models that could improve survival outcomes for this demographic.
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Background: Preterm birth (PTB) is a serious health problem. PTB complications is the main cause of death in infants under five years of age worldwide. The ability to accurately predict risk for PTB during early pregnancy would allow early monitoring and interventions to provide personalized care, and hence improve outcomes for the mother and infant.

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The disparity in scale, complexity, and control level between laboratory experiments and field observational studies has shaped both the methodologies employed and the nature of the research questions pursued in ecology and hydrology. While lysimeters and fabricated ecosystems suitably fit in this gap, their use as mesoscale experimental facilities has not been fully explored because of the limited manipulating capabilities and integration with imaging and monitoring methods, particularly for soil functioning. The proposed fabricated ecosystem (4.

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  • The cortical thick ascending limb (CTAL) of the kidney was first characterized by Maurice Burg in 1973, revealing its role in actively reabsorbing NaCl while having low water permeability, allowing it to produce dilute urine during high water intake.
  • In the 1980s, Greger and Schlatter identified the specific membrane transport processes for NaCl, which were further characterized at the molecular level by various researchers in the 1990s using cDNA cloning and advancements in genome sequencing.
  • By the 2010s, mathematical models were developed to explore CTAL transport mechanisms, leading to investigations into Burg's 'static head' phenomenon, the adaptation of short CTALs in juxtamedullary nephrons,
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