Diagnostic accuracy of breast MRI for patients with suspicious nipple discharge and negative mammography and ultrasound: a prospective study.

Objectives: To evaluate the diagnostic accuracy of breast MRI in identifying lesions requiring excision for patients with suspicious nipple discharge but normal mammograms and ultrasounds.

Methods: Between September 2013 and May 2019, 106 female participants (mean age 57.9 years) were consecutively included in this prospective multicenter study; 102 were retained for analysis.

Preoperative Breast Magnetic Resonance Imaging in Women With Local Ductal Carcinoma in Situ to Optimize Surgical Outcomes: Results From the Randomized Phase III Trial IRCIS.

Purpose: We evaluated the addition of breast magnetic resonance imaging (MRI) to standard radiologic evaluation on the re-intervention rate in women with ductal carcinoma in situ (DCIS) undergoing breast-conserving surgery.

Patients And Methods: Women with biopsy-proven DCIS corresponding to a unifocal microcalcification cluster or a mass less than 30 mm were randomly assigned to undergo MRI or standard evaluation. The primary end point was the re-intervention rate for positive or close margins (< 2 mm) in the 6 months after randomization ( ClinicalTrials.

A rare case of a giant ulcerated benign phyllode tumor.

Phyllode tumors are rare fibroepithelial neoplasms divided into three histological grades according to their potential for malignancy. Low grade tumors are usually smaller with a slower evolution. We present here the case of a 40 year old women presenting an augmentation over one month of the volume of her right breast with an ulcerated mass measuring 25cm.

Clinical practice guidelines from the French College of Gynecologists and Obstetricians (CNGOF): benign breast tumors - short text.

Screening with breast ultrasound in combination with mammography is needed to investigate a clinical breast mass (Grade B), colored single-pore breast nipple discharge (Grade C), or mastitis (Grade C). The BI-RADS system is recommended for describing and classifying abnormal breast imaging findings. For a breast abscess, a percutaneous biopsy is recommended in the case of a mass or persistent symptoms (Grade C).

[Management of breast nipple discharge: Recommendations].

Objectives: To investigate diagnostic value of imaging procedures and management strategies of the patients with nipple discharge (ND) to establish management recommendations.

Methods: Bibliographical search in French and English languages by consultation of PubMed, Cochrane and Embase databases.

Results: Although, all ND require an systematic evaluation guided by clinical data, bloody ND could be a predictor of breast cancer risk among different colors of discharge particularly in patients of more than 50 years (LE2).

[Benign breast tumors: Recommendations of Collège National des Gynécologues Obstétriciens Français (CNGOF)--Short text].

Breast sonography is required with mammogram to explore clinical breast mass (grade B), colored unipore breast nipple discharge (grade C), or mastitis (grade C). Bi-RADS system is recommended to describe and classify breast-imaging abnormalities. For breast abscess, a percutaneous biopsy is recommended in case of mass or persistent symptoms (grade C).

[Breast imaging of mass, architectural distortion and asymmetry: Clinical practice guidelines].

The development of the mammary imaging (mammography, ultrasound, MRI) enables the discovery of more and more lesions. The BI-RADS lexicon is the reference book for their descriptive analysis. Four elementary images must be individualized: masses and architectural distortion described in 3 imaging techniques, asymmetries and microcalcifications described in mammography.

[Explorations of breast microcalcifications: Guidelines].

Objectives: To assess imaging performances for the detection, characterization and biopsy of breast microcalcifications and make recommendations.

Materials And Methods: French and English publications were searched using PubMed, Cochrane Library and international learned societies recommendations.

Results: Digital mammography (DR [Direct Radiography] and CR [Computed Radiography]) and screen-film mammography demonstrate good performances for the detection and the characterization of breast microcalcifications.

[Clinical practice guidelines: Benign breast tumor--Aims, methods and organization].

Conversely to breast cancer, few data and guidelines are available to explore and manage benign breast disorders. Therefore, the Collège national des gynécologues et obstétriciens français (CNGOF - French College of Gynaecologists and Obstetricians) decided to establish clinical practice guidelines for benign breast tumour (BBT). CNGOF appointed a committee with responsibility for selecting experts, compiling questions and summarizing the recommendations.

Breast MR biopsy: Pathological and radiological correlation.

Purpose: To identify pathological features for sample analysis of magnetic resonance imaging-guided vaccum-assisted breast biopsy (MRIgVaBB) to optimize radio pathological correlation and identify discordant benign result.

Material And Methods: Databases of two centres were queried to identify MRIgVaBB performed between January 2009 and February 2013. A cohort of 197 women (mean age: 54.

[Pregnancy after cancer: for whom and when?].

Planning a pregnancy for patients with a history of cancer, including breast cancer, is a clinical situation that becomes more and more common. Several specific items are to be discussed: decrease of fertility after cancer treatment, fertility preservation options, impact of pregnancy on cancer recurrence risk and appropriate interval between cancer and pregnancy. Programming pregnancy after cancer is doable in a multidisciplinary setting, and begins at cancer diagnosis to anticipate the various specific pitfalls.

Added value of one-view breast tomosynthesis combined with digital mammography according to reader experience.

Purpose: To retrospectively evaluate the added value of one-view breast tomosynthesis in adjunct with mammography to characterize breast lesions.

Materials And Methods: Our institutional ethics committees approved the study and granted a waiver of informed consent. One hundred fifty-five women (mean age, 51.

Standardized diagnosis and reporting of breast cancer.

Standardized terminology developed by the American College of Radiography (ACR) through the Breast-Imaging Reporting and Data System (BI-RADS) lexicon is used worldwide to describe the findings of the various breast-imaging techniques (mammography, ultrasound, and magnetic resonance imaging (MRI)). A 7-level positive predictive value (PPV) of malignancy classification system (from BI-RADS category 0 to category 6) has been based on this terminology, giving imaging a central role in the diagnostic strategy. This document presents the standardized, compulsory BI-RADS terminology used in breast-imaging reports in 2013 in view of the new edition that will be published at the end of the year.

[Delays in treatment of breast cancer: experience of an expert center of the Assistance Publique-Hôpitaux de Paris (AP-HP)].

Objectives: The National Institute of the Cancer (INCA) recently published a study over the deadlines of medical care of breast cancers. We compared our delay within the framework of our expert center with their results.

Patients And Methods: Our work is a retrospective unicentric non-interventional study.

Radiopathological correlations: masses, non-masslike enhancements and MRI-guided biopsy.

MRI-guided biopsy is a recent interventional breast technique. Validating the procedure poses a new problem because the signal targeted is created by the injection of a paramagnetic contrast agent and is thus transitory. In the first instance, the procedure is validated by the radiologist, who checks that targeting is accurate and inserts a clip at the end of the procedure, and secondly by analysis of the histopathological results, which should be representative of the lesion.

How to measure breast cancer tumoral size at MR imaging?

Objective: To compare the accuracy of different MR sequences to measure tumor size.

Methods: Eighty-six women (mean age: 53 years (30-78)) who underwent preoperative MRI for breast cancer were included. Maximal diameters of the index tumor (IT) and of the whole extent of the tumor (WET) were measured on T2-weighted (T2W) sequences, on dynamic contrast-enhanced (DCE) T1-weighted (T1W) sequences and on Maximal Intensity Projection (MIP) reconstructions.

Current opinion on clip placement after breast biopsy: a survey of practising radiologists in France and Quebec.

Aim: To investigate current practice regarding clip placement after breast biopsy.

Materials And Methods: In June 2011, an online survey instrument was designed using an Internet-based survey site (www.surveymonkey.

[Are decisions of multidisciplinary tumor boards in accordance with the guidelines? Experience of an university reference center for breast cancer].

Objective: Multidisciplinary meeting (MDM) should ensure a homogeneous management of the patients by following breast cancer guidelines. Are these guidelines really applied in MDM decisions?

Patients And Methods: We reviewed the last 200 cases of patients operated in our department for breast cancer. We searched for each case if MDM had been consulted, at which step of the management and if the decision was in accordance with our guidelines.

Tips and techniques in breast MRI.

The standard breast MRI protocol includes T2 sequences (anatomy and signal analysis), T1 gradient-echo sequences which can detect markers placed after biopsy, and injected dynamic 3D sequences for performing volume and multiplanar reconstructions, which are particularly useful for locating lesions well. Good patient positioning is essential and is obtained by using foam wedges for small breasts, ensuring there are no folds, and the correct position of the nipples. These aspects limit movement artefacts which alter subtraction sequences, so that it must always be possible for reading these sequences to be assisted by comparing them with the native sequences.

Predictive factors for breast cancer in patients diagnosed with ductal intraepithelial neoplasia, grade 1B.

Background: For ductal intraepithelial neoplasia, grade 1B, studies that predict breast cancer risk after an 11-gauge vacuum-assisted breast biopsy have yielded contradictory results. In order to identify a predictive model of breast cancer risk, we assessed the underestimation rate according to radiological and clinical findings.

Patients And Methods: Our study involved 212 patients.

Diffusion-weighted MR imaging of the breast: advantages and pitfalls.

The aim of this paper is to review all clinical applications of diffusion weighted MR imaging (DWI) for breast pathology. The challenge of DWI is to obtain the best compromise between lesion detection and characterization. Technical factors affecting lesion characterization and detection are detailed including the effect of contrast administration, the choice of number of b and of b(max), the variation of diagnostic performance according to the type and the size of lesion studied.

Comparison of two nomograms to predict pathologic complete responses to neoadjuvant chemotherapy for breast cancer: evidence that HER2-positive tumors need specific predictors.

The aim of this study is to compare two published nomograms, the "Institut Gustave Roussy/M.D. Anderson Cancer Center" (IGR/MDACC) and the Colleoni nomograms, in predicting pathologic complete responses (pCR) to preoperative chemotherapy in an independent cohort and to assess the impact of HER2 status.

[Breast MRI: Artefacts and pitfalls].

Multiple artefacts and pitfalls may occur with breast MRI. Artefacts are secondary to the MR technique itself while pitfalls often are the result of human error. The most common artefacts include motion, pulsation, chemical shift and magnetic susceptibility.