Low serum 25-hydroxyvitamin D level: an independent risk factor for tuberculosis?

Background & Aims: Vitamin D deficiency has been associated with an increased risk of tuberculosis (TB). Low serum vitamin D levels may also be associated with poor nutritional status in TB patients. Therefore, this study aimed at evaluating the association between low serum vitamin D level and TB, regardless of other nutritional factors.

CD4(+)FoxP3(+) T regulatory cells in drug-susceptible and multidrug-resistant tuberculosis.

Regulatory T cells (Treg) increase in active tuberculosis (TB). However, whether Treg-mediated immune suppression affect the susceptibility to active TB or development of multidrug-resistant (MDR) TB is not yet clear. We compared circulatory Treg frequencies in drug susceptible (DS) and MDR TB before and after anti-TB treatment.