Publications by authors named "Choo V"
Article Synopsis
- A systematic review and meta-analysis were conducted to investigate how food sources of fructose-containing sugars affect blood pressure (BP) under different energy control conditions.
- Out of 147 trials involving over 5,200 participants, it was found that excess energy from fructose-containing sugars decreased BP when sugar was added but had no significant effects during substitution, subtraction, or free intake trials.
- The results suggest that consuming fruit and 100% fruit juice at low levels may help lower BP, while high doses of mixed sources, especially sugar-sweetened beverages, can increase BP, highlighting the influence of food source and energy balance on BP outcomes.
Background: Sugar-sweetened beverages (SSBs) providing excess energy increase adiposity. The effect of other food sources of sugars at different energy control levels is unclear.
Objectives: To determine the effect of food sources of fructose-containing sugars by energy control on adiposity.
Article Synopsis
- Research explores the link between fructose-containing sugars in sugar-sweetened beverages (SSBs) and inflammatory markers, focusing on food source and energy control.
- A systematic review analyzed 64 controlled trials, looking at how different fructose sources (like sweetened dairy and fruit juice) affect inflammation over varying energy levels.
- Findings indicate that total fructose-containing sugars reduced C-reactive protein (CRP) in addition trials, while other trial types showed no significant effects on inflammation, suggesting the food source plays a critical role.
Article Synopsis
- Excess fructose from sugar-sweetened beverages (SSBs) is linked to increased markers of non-alcoholic fatty liver disease (NAFLD), but the impact of other fructose sources is unclear.
- The review encompassed 51 trials involving various food sources of fructose, focusing on their effects on intrahepatocellular lipid (IHCL), alanine aminotransferase (ALT), and aspartate aminotransferase (AST).
- Findings showed that total fructose increased IHCL in addition trials but had no significant effects in substitution or ad libitum trials, and that SSBs were particularly effective in raising IHCL and ALT levels.
Background: Although fructose as a source of excess calories increases uric acid, the effect of the food matrix is unclear.
Objectives: To assess the effects of fructose-containing sugars by food source at different levels of energy control on uric acid, we conducted a systematic review and meta-analysis of controlled trials.
Methods: MEDLINE, Embase, and the Cochrane Library were searched (through 11 January 2021) for trials ≥ 7 days.
Background: Perhaps, as never before, we need innovators. With our growing population numbers, and with increasing pressures on our education systems, are we in danger of becoming more rigid and formulaic and increasingly inhibiting innovation? When young can we predict who will become the great innovators? For example, in medicine, who will change clinical practice?
Aims: We therefore determined to assess whether the current academic excellence approach to medical school entrance would have captured previous great innovators in medicine, assuming that they should all have well fulfilled current entrance requirements.
Methods: The authors assembled a list of 100 great medical innovators which was then approved, rejected or added to by a jury of 12 MD fellows of the Royal Society of Canada.
Objective: To assess the effect of different food sources of fructose-containing sugars on glycaemic control at different levels of energy control.
Design: Systematic review and meta-analysis of controlled intervention studies.
Data Sources: Medine, Embase, and the Cochrane Library up to 25 April 2018.
Background & Aims: To update the European Association for the Study of Diabetes (EASD) clinical practice guidelines for nutrition therapy, we conducted a systematic review and meta-analysis of randomized controlled trials to summarize the evidence for the effect of vegetarian dietary patterns on glycemic control and other established cardiometabolic risk factors in individuals with diabetes.
Methods: We searched MEDLINE, EMBASE, and Cochrane databases through February 26, 2018 for randomized controlled trials ≥3 weeks assessing the effect of vegetarian dietary patterns in individuals with diabetes. The primary outcome was HbA.
Background: Obesity is a risk factor for developing several diseases, and although dietary pulses (nonoil seeds of legumes such as beans, lentils, chickpeas, and dry peas) are well positioned to aid in weight control, the effects of dietary pulses on weight loss are unclear.
Objective: We summarized and quantified the effects of dietary pulse consumption on body weight, waist circumference, and body fat by conducting a systematic review and meta-analysis of randomized controlled trials.
Design: We searched the databases MEDLINE, Embase, CINAHL, and the Cochrane Library through 11 May 2015 for randomized controlled trials of ≥3 wk of duration that compared the effects of diets containing whole dietary pulses with those of comparator diets without a dietary pulse intervention.
Background: Select trials of fructose overfeeding have been used to implicate fructose as a driver of cardiometabolic risk.
Objective: We examined temporal trends of fructose dose in human controlled feeding trials of fructose and cardiometabolic risk.
Methods: We combined studies from eight meta-analyses on fructose and cardiometabolic risk to assess the average fructose dose used in these trials.