Publications by authors named "Chongwen Guo"
Article Synopsis
- Deoxynivalenol (DON) is a harmful mycotoxin that contaminates cereal crops and animal feed, posing health risks to both humans and animals.
- Recent research identified a new bacterium, sp. D-G15, capable of degrading DON into less toxic compounds, with specific enzymes playing key roles in this process.
- The study also highlighted that the ability to synthesize pyrroloquinoline quinone (PQQ) is a unique trait of DON-degrading strains, which could be leveraged for developing technologies to detoxify DON in the food industry.
Deoxynivalenol (DON) is the most frequently contaminated mycotoxin in food and feed worldwide, causing significant economic losses and health risks. Physical and chemical detoxification methods are widely used, but they cannot efficiently and specifically remove DON. In the study, the combination of bioinformatics screening and experimental verification confirmed that sorbose dehydrogenase (SDH) can effectively convert DON to 3-keto-DON and a substance that removes four hydrogen atoms for DON.
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