Publications by authors named "Chongwan Wei"
The heat stress (HS) induced by high temperatures can result in oxidative damage to muscles, thereby compromising both muscle growth and immune function within the organism. Mitophagy serves as a pivotal pathway in alleviating excessive ROS production and subsequent oxidative damage. However, the potential role of epigallocatechin-3-gallate (EGCG), a natural antioxidant found in tea, in mitophagy under HS remains unexplored.
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- Four groups of castrated boars were fed different levels of RES to determine its impact, with doses of 400 mg and 600 mg per kg significantly enhancing meat quality and antioxidant enzyme activity.
- Molecular dynamics indicated RES directly interacts with KEAP1, affecting the KEAP1-NRF2 interaction, while RNA sequencing identified lncRNAs linked to improved antioxidant capacity, highlighting RES's role in enhancing meat quality through the KEAP1-NRF2 pathway.
Resveratrol (RES) is one of the best-known bioactive polyphenols that has received much attention in recent years because of its importance to anti-obesity. However, the exact mechanism underlying this effect and whether it can improve lipid metabolism by regulating the long-chain noncoding RNA (lncRNA) remains unclear. In this study, 24 healthy crossbred castrated boars were fed a basal diet (control) and a basal diet supplemented with 200 mg, 400 mg or 600 mg RES per Kilogram (kg) of feed for 41 d, respectively.
View Article and Find Full Text PDFAims: Our study aimed to evaluate the effects of different dosages of sodium butyrate and niacin on the growth performance, faecal Vitamin B and microbiota in weaned piglets.
Methods And Results: Seventy-two weaned piglets (Duroc × Landrace × Yorkshire, age of 21 days) were randomly assigned to one of six treatments (12 pigs/treatment); the control (CT) group was administered a basal diet. The groups in which concentration ratios of sodium butyrate to niacin were 100: 1, 100: 2, 100: 4, 100: 8 and 100: 16 (BN1, BN2, BN4, BN8 and BN16) were administered a basal diet supplemented with 2000 mg kg sodium butyrate and 20, 40, 80, 160 or 320 mg·kg niacin.