Synopsis of recent research by authors named "Chonglu Li"
- Chonglu Li's recent research primarily centers on the development of innovative metallacycle-based compounds, particularly those involving ruthenium (Ru) and platinum (Pt), aimed at enhancing the effectiveness of sonodynamic therapy (SDT) and immunogenic cell death (ICD) for treating multidrug-resistant biofilms and deep-seated tumors.
- His studies focus on overcoming challenges in therapeutic efficacy related to complex biological environments, utilizing strategies such as π-expansion for optimizing sonosensitizers and phototherapy agents that generate reactive oxygen species (ROS) under specific conditions.
- Li's work also emphasizes the importance of enhancing selectivity between tumor and normal cells while achieving deep tissue penetration, contributing to improved safety and reduced side effects, thus paving the way for more effective cancer treatments.