Publications by authors named "Chonghui Jia"
Article Synopsis
- The CRL4 complex, involving DTL, is crucial for regulating epidermal progenitor cells' balance between proliferation and differentiation during skin development.
- DTL deficiency leads to issues such as improper epidermal layers and hair follicle loss, linked to disrupted cell cycle and increased apoptosis in epidermal cells.
- The study highlights that while DTL affects skin development malformations, its influence on cell proliferation and differentiation is independent of the p53 pathway.
