Sheng Wu Gong Cheng Xue Bao
September 2024
Gadusol, an efficient natural ultraviolet (UV) absorbing substance with antioxidant capacity, is ubiquitous in aquatic organisms such as microorganisms, algae, and fish eggs. In order to address issues such as its low natural extraction yield and environmental unfriendliness, we introduced the gadusol synthesis pathway from zebrafish into and successfully constructed the recombinant strain capable of synthesizing gadusol. The xylose assimilation genes derived from were further introduced into the recombinant strain to increase the content of the key substrate sedoheptulose 7-phosphate (S7P).
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