Publications by authors named "Chong-kai Gao"
[Study on self-microemulsifying membrane controlled-release drop pill of hawthorn leaves flavonoids].
Zhongguo Zhong Yao Za Zhi
March 2014
Article Synopsis
- The study focused on creating a self-microemulsifying membrane-controlled release drop pill for hawthorn leaves flavonoids to enhance their dissolution and improve bioavailability.
- The pill was formulated using various components, including polyethylene glycol and ethyl cellulose, leading to a sustained release of flavonoids over 12 hours.
- In tests involving rats, the self-microemulsifying drop pill showed a 2.47 times higher bioavailability compared to quick-release formulations, demonstrating its effectiveness.
Objective: To establish an optimum enrichment and purification process of total flavonoids in Microcos paniculata by macroporous resins.
Methods: Five kinds of resins were compared and the best one was chosen. Then the parameters of the process were optimized by single factor tests, uniform design and statistical methods.
Aim: To study the chemical constituents of Paeonia lactiflora.
Methods: The constituents of P. lactiflora were separated by using various kinds of modern chromatography and was identified its structure on the basis of spectral analysis.