Melittin treatment prevents colorectal cancer from progressing in mice through ER stress-mediated apoptosis.

Objectives: The primary goal of the current study was to investigate the effect of melittin on colorectal cancer (CRC).

Methods: The viability of cancer cells was tested using the MTT assay, and the apoptosis of tumour cells was assayed using Annexin V/PI staining in vitro or TUNEL staining in vivo. The in vivo toxicity and efficacy of melittin were assessed in a xenograft mouse model.

Application of continuous nursing intervention for patients with PICC catheterization undergoing tumor chemotherapy.

Objective: To explore the effect of continuous nursing service on the self-care agency score, catheter indwelling time, on-time maintenance ratio, and patients' complication rates with tumor chemotherapy PICC catheterization.

Methods: According to the nursing methods, a total of 90 cancer patients undergoing chemotherapy in our hospital from July 2018 to July 2020 were divided into an observation group (n=45) and a control group (n=45). The control group received conventional nursing care; which was also given to the observation group in addition to continuous nursing service.