Publications by authors named "Chong-Hao Zhong"
J Biomed Mater Res A
April 2015
Article Synopsis
- This study explored a detergent-enzymatic decellularization (DEM) method on rabbit tracheas to create matrices for organ reconstruction, focusing on their integrity, mechanical properties, and biocompatibility.
- Results showed that after seven cycles of decellularization, most cells and antigenicity were eliminated, while maintaining the structure and mechanical characteristics of the original trachea.
- Implantation of these bioengineered matrices in rats led to lower inflammation and no increased immune response, indicating their potential as effective substitutes for natural tracheas.
