IL-8-induced CXCR2 down-regulation in circulating monocytes in hepatocellular carcinoma is partially dependent on MAGL.

Background: CXC-chemokine receptor 2 (CXCR2) expression was found to be down-regulated on circulating monocytes of cancer patients. Here, we analyze the percentage of CD14CXCR2 monocyte subsets in hepatocellular carcinoma (HCC) patients, and investigate the mechanisms that regulate CXCR2 surface expression on monocytes and its biological function.

Methods: Flow cytometry was used to analyze the proportion of the CD14CXCR2 subset from the total circulating monocytes of HCC patients.

Application of pancreaticojejunostomy with one-layer suture in pancreaticoduodenectomy: A retrospective cohort study.

Background: Postoperative pancreatic fistula (POPF) is the most common critical complication after pancreaticoduodenectomy (PD) and a primary reason for increased mortality and morbidity after PD. To perform a safe pancreaticojejunostomy (PJ), a fast and simple technique of duct-to-mucosa PJ with one-layer suture was devised at our institution.

Materials And Methods: We conducted a retrospective analysis of 81 successive cases of PD performed at our hospital from March 2012 to August 2016.

Hepatocyte infusions improve the results of liver transplantation in rats.

Background/aims: The results of liver transplantation were influenced by miscellaneous factors. The aim was the notion that hepatocyte infusions might improve results of liver transplantation in rats.

Methodology: Survival, serum analytes, FasL production, and histologic degree of rejection of transplanted rats pretreated with hepatocyte infusions (Hepatocyte) was compared to that of rats pretreated with either bone marrow cell infusions (Marrow) or saline infusions (Control).

Hemodialysis-induced hyperglycemia after liver transplantation.

Background/aims: One might hypothesize that hemodialysis, by cleansing the blood of metabolic waste, might elevate the patient's sensitivity to insulin. The results of this study show that hypothesis is untrue in the case of liver transplant patients.

Methodology: Glucose levels of five liver transplant patients, whom underwent 24 hemodialysis sessions in total, were compared with that of five non-liver transplantation patients, whom had undergon 21 hemodyalisis sessions in total.

Loss expression of active fragile sites genes associated with the severity of breast epithelial abnormalities.

Background: WWOX and FHIT are two candidate tumor suppressor genes located in active fragile sites, the damage of which has been associated with the development of breast cancer. The association of the expression of these genes and the development of breast cancer has not been fully explored. We evaluated mRNA and protein expression of WWOX and FHIT in breast tissue with normal histological appearances, atypical ductal hyperplasia, ductal carcinoma in situ, and invasive cancer to see if a progressive decline in expression was present.

Ileal transposition controls diabetes as well as modified duodenal jejunal bypass with better lipid lowering in a nonobese rat model of type II diabetes by increasing GLP-1.

Objective: Modified duodenal jejunal bypass (MDJB) and ileal transposition (IT) were compared as surgeries for glucose control. Initial conclusions might be formed with respect to the possibility of (1) whether duodenal exclusion is essential for the control of diabetes and (2) application as a low morbid procedure.

Summary Background Data: IT, MDJB, sham-IT, and sham-MDJB procedures were performed on 10- to 12-week-old Goto-Kakizaki (GK) rats, nonobese animals who spontaneously develop type 2 diabetes.

Influence of estrogen and androgen on the outcome of liver transplantation.

Background/aims: To assess influence of sex hormone on outcome of orthotropic liver transplantation (OLT).

Methodology: Adult female Wistar rats were used as donors and male Wistar rats as recipients. Two experimental series were established.

[Clinical evaluation of laparoscopic common bile duct exploration in 587 cases].

Objective: To summarize the experience of laparoscopic common bile duct exploration.

Methods: The clinical data of 587 cases who underwent laparoscopic common bile duct exploration from June 1992 to May 2006 were analyzed.

Results: The surgery was successful in 585 cases (99.