Publications by authors named "Chong S E Lim"
Objective: The diagnosis of axial spondyloarthritis (axSpA) is hampered by diagnostic delay. Computed tomography (CT) undertaken for nonmusculoskeletal (non-MSK) indications in patients with inflammatory bowel disease (IBD) offers an opportunity to identify sacroiliitis for prompt rheumatology referral. This study aims to identify what proportion of patients with IBD who underwent abdominopelvic CT for non-MSK indications have axSpA and to explore the role of a standardized screening tool to prospectively identify axSpA on imaging.
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- - The study aimed to identify how many patients at IBD clinics experience undiagnosed axial spondyloarthritis (RVD-axSpA) while suffering from chronic back pain.
- - Out of 470 patients surveyed, 91 reported chronic back pain; 82 met criteria for further rheumatology assessment, revealing an estimated 5% prevalence of undiagnosed RVD-axSpA in this group.
- - The findings suggest a significant number of IBD patients may have this condition without knowing it, highlighting the need for better referrals from gastroenterology to improve diagnosis and treatment access.
The clinical utility of human leucocyte antigen B27 in axial spondyloarthritis.
Rheumatology (Oxford)
June 2018
The association between HLA-B27 and AS was first established in the early 1970s. Since then, our understanding of this disease has changed, such that we now recognize AS to be the extreme of the clinical phenotype within a disease spectrum known as axial SpA (axSpA). Recent advances in therapeutic options have driven the need for earlier diagnosis and many screening strategies have been proposed to facilitate this.
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