Correlation of 18F-FDG PET/CT SUVmax with clinical features, D-dimer and LDH in patients with primary intestinal lymphoma.

Objective: To investigate the characteristics of fluorine-18-deoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) maximum standardized uptake value (SUVmax) in primary intestinal lymphoma (PIL) and its correlation with D-dimer and lactate dehydrogenase (LDH).

Methods: Fifty-two patients diagnosed with PIL from June 2016 to December 2019 were analyzed. All patients underwent 18F-FDG PET/CT.

Neoantigen vaccination induces clinical and immunologic responses in non-small cell lung cancer patients harboring EGFR mutations.

Background: Neoantigen (NeoAg) peptides displayed at the tumor cell surface by human leukocyte antigen molecules show exquisite tumor specificity and can elicit T cell mediated tumor rejection. However, few NeoAgs are predicted to be shared between patients, and none to date have demonstrated therapeutic value in the context of vaccination.

Methods: We report here a phase I trial of personalized NeoAg peptide vaccination (PPV) of 24 stage III/IV non-small cell lung cancer (NSCLC) patients who had previously progressed following multiple conventional therapies, including surgery, radiation, chemotherapy, and tyrosine kinase inhibitors (TKIs).

Semipermeable membrane device-assisted desorption of pyrene from soils and its relationship to bioavailability.

Desorption of pyrene from three different soils was studied using a semipermeable membrane device (SPMD)-assisted method to develop a new approach to predict bioavailability of hydrophobic organic compounds (HOCs) in soils. The results showed that pyrene desorption increased with reduction of soil organic matter content and elevation of pyrene concentration in unaged soils, and the 50-d desorption percentage was 52.2 +/- 3.

[Desorption of polycyclic aromatic hydrocarbons in soils assisted by SPMD].

In order to develop a new method to study the desorption and bioavailability of hydrophobic organic chemicals (HOCs) in soils, a method using semi-permeable membrane device (SPMD) to study desorption of HOCs in soils has been set up, and assisted desorption of polycyclic aromatic hydrocarbons (PAHs), phenanthrene(PHE), pyrene(PYE), and benzo[a] pyrene (B[a]PYE) in three different kinds of soils was studied using SPMD. The results show that SPMD is a good measurement to study the desorption and bioavailability of HOCs in soils. SPMD assisted desorption of PAHs is highly dependent on the properties of the soils and the chemicals.