With the explosive growth of terminal devices, scheduling massive parallel task streams has become a core challenge for distributed platforms. For computing resource providers, enhancing reliability, shortening response times, and reducing costs are significant challenges, particularly in achieving energy efficiency through scheduling to realize green computing. This paper investigates the heterogeneous parallel task flow scheduling problem to minimize system energy consumption under response time constraints.
View Article and Find Full Text PDFTwo years ago, the patient suffered from type A aortic dissection. As a result, partial aortic dissection artificial vascular replacement and partial aortic arch artificial vascular replacement were performed. Six months after the operation, an anastomotic fistula in the ascending aorta was detected, which subsequently progressed to chronic heart failure of New York Heart Association (NYHA grade) class III.
View Article and Find Full Text PDFExcessive exercise can lead to physical fatigue and disruption of the antioxidant system, resulting in neurological damage and cognitive decline. Cordycepin, the main component of Cordyceps militaris, has anti-inflammatory, antioxidant and neuroprotective effects. In this study, the anti-fatigue effect and potential mechanism of action of cordycepin were investigated using a forced exercise mouse model.
View Article and Find Full Text PDFBiomineralization, a key driving force underlying dramatic morphological diversity, is widely adopted by metazoans to incorporate inorganic minerals into their organic matrices. The scaly-foot snail Chrysomallon squamiferum from deep-sea hot vents uniquely possesses hundreds of sclerites on its foot in addition to a coiled shell, providing an exclusive case to study the formation of evolutionarily novel hard parts. Here, we identified the matrix proteins present in the exoskeletons of C.
View Article and Find Full Text PDFExtreme morphological disparity within Mollusca has long confounded efforts to reconstruct a stable backbone phylogeny for the phylum. Familiar molluscan groups-gastropods, bivalves, and cephalopods-each represent a diverse radiation with myriad morphological, ecological, and behavioral adaptations. The phylum further encompasses many more unfamiliar experiments in animal body-plan evolution.
View Article and Find Full Text PDFThe immunosuppressive tumor microenvironment (TME) shaped by tumor-associated macrophages (TAMs) is essential for lung adenocarcinoma (LUAD) immune tolerance and tumor progression. Here, we first reported that proteinase 3 (PRTN3) promoted the alternative activation (M2) of TAMs and enhanced IL33/regulatory T cells (Tregs)-mediated tumor immunosuppression in LUAD. Firstly, clinical analysis revealed PRTN3 was highly expressed in TAMs and correlated with the tumor progression and poor prognosis in LUAD patients.
View Article and Find Full Text PDFThe investigation of layered rock mechanical properties is important for rock stability analysis. To examine the effects of layer inclination angle (LIA) and layer thickness (LT) on the compressive mechanical properties and damage mechanism of layered rock, this paper proposes a new method of preparing layered rock specimens using similar materials and conducting uniaxial compression tests. At the same time, PFC2D numerical analysis software is used to establish the discrete element numerical model of layered rock under uniaxial compression to deepen its microscopic damage mechanism.
View Article and Find Full Text PDFIntroduction: () is one of the most important zoonotic pathogens and can be transmitted to humans through the meat diet routes, causing necrotising pneumonia.
Methods: This study investigated the therapeutic effect of bacteriophage lysin LysGH15 on necrotising pneumonia in rabbit model caused by .
Results: In the experiments, 50 μg/mL LysGH15 not only significantly reduced the viable count (approximately 3.
Cycloaddition, as a sound strategy for high-value utilization of carbon dioxide (CO), has been long pursued, wherein the challenging substrate activation process is a top priority for devising novel heterogeneous catalysts. In this study, a guanidine-based ionic liquid tethering -NH groups was designed and integrated with chromium (III) terephthalate (MIL-101(Cr)) through the coordination with unsaturated Cr centers. The developed [NHTMG]Br@MIL-101(Cr) (TMG represents tetramethylguanidine) decorated with plentiful basic functional groups created a fast channel for the capturing and binding of CO, while the highly-accessible Lewis acidic sites (Cr) and hydrogen bond donors (N-H) embedded within the nanocomposite synergized to activate the epoxide, synchronously.
View Article and Find Full Text PDFBackground: Touch comfort refers to the level of comfort nurses feel internally when touching patients. Good touch comfort indicates that nurses feel very comfortable during such interactions. With the steady advancement of the "Healthy China" initiative, there is an increasing demand for humanistic care.
View Article and Find Full Text PDFConventional SiC alpha particle radiation detectors typically operate under an applied bias of tens to hundreds of volts. This study introduces a self-powered alpha particle detector using an AlScN/SiC heterojunction structure. By optimizing the thickness of the AlScN film, the detector achieves a low dark current (1.
View Article and Find Full Text PDFDelectopecten is a small genus of the family Pectinidae (Bivalvia: Pectinida) that remains poorly studied in terms of both morphology and phylogeny. Here, we describe the first member of this genus from deep-sea hydrothermal vent ecosystems, D. thermus sp.
View Article and Find Full Text PDFAs an emerging photovoltaic material, antimony selenosulfide (Sb(S,Se)) has attracted considerable attention and research enthusiasm. However, the current solution-processed Sb(S,Se) layers suffer from severe unfavorable energy band structure problems attributed to the vertical gradient-variable Se/S atomic ratio, making it a challenging and prospective subject. Herein, a novel and convenient alkali metal Cs-induced Se/S atomic ratio variation strategy has been developed for the first time to regulate Sb(S,Se) energy band structure through hydrothermal-processed CdS nanorod-arrays (NAs)/Sb(S,Se) bulk heterojunction (BHJ) films.
View Article and Find Full Text PDFBackground: This study aimed to analyse the relationship of the blood lipid profile and interleukin-6 (IL-6) with osteoporosis and osteopenia and to explore the predictive value of the combined application of these biomarkers in osteoporosis and osteopenia.
Methods: Data from 276 patients treated in the orthopaedics department were retrospectively analysed. Their general information was collected, and the relationships among the blood lipid profile, IL-6 with bone turnover markers, and bone mineral density (BMD) were analysed.
Unlabelled: The rapid sequence typing (ST) of bacterial strains is crucial for effective nosocomial infection control and mitigating the spread of nosocomial pathogens, e.g., .
View Article and Find Full Text PDFAdropin is a secreted peptide encoded by the energy homeostasis-associated gene (ENHO), located chromosome 9p13.3, with a conserved amino acid sequence across humans and mice. Its expression is regulated by various factors, including fat, LXRα, ERα, ROR, and STAT3.
View Article and Find Full Text PDFBiological clocks are a ubiquitous feature of all life, enabling the use of natural environmental cycles to track time. Although studies on circadian rhythms have contributed greatly to the knowledge of chronobiology, biological rhythms in dark biospheres such as the deep sea remain poorly understood. Here, based on a free-running experiment in the laboratory, we reveal potentially endogenous rhythms in the gene expression of the deep-sea hydrothermal vent shrimp .
View Article and Find Full Text PDFIntroduction: The effects of remimazolam (Re) in combination with andrographolide (AP) on learning, memory, and motor abilities in rats following cardiopulmonary bypass (CPB) surgery were studied.
Methods: We hypothesized that the combination of Re and AP could improve postoperative cognitive dysfunction (POCD) in rats after CPB by modulating nervous system inflammation. Cognitive function was assessed using the Morris Water Maze test, and the concentrations of tumor necrosis factor alpha (TNF-α), interleukin-1 beta (IL-1β), and interleukin-6 (IL-6) in serum were measured by enzyme-linked immunosorbent assay (ELISA).
The aim of this study was to investigate the loss of docosahexaenoic acid (DHA) from three supplements (two powders and one oil) after digestion (rumen and gastrointestinal) and their effects on the number and composition of rumen bacteria, using an in vitro approach. The concentration of supplements has a significant impact on the DHA loss rate and algal oil exhibited the highest rate of loss, but bioaccessibility was not significantly different from the other supplements. 16S rRNA sequencing showed that three DHA supplements altered the bacterial composition of in vitro batch cultures inoculated with rumen microorganisms from cows, and caused changes in the relative abundance of important bacterial phyla, families, and genera.
View Article and Find Full Text PDFBackground: The 3-hydroxybutyrate dehydrogenase 1 (BDH1) mainly participates in the regulation of milk fat synthesis and ketone body synthesis in mammary epithelial cells. In our previous study, BDH1 was identified as a key candidate gene regulating lipid metabolism in mammary glands of dairy goats by RNA-seq. This study aimed to investigate the effect of BDH1 on lipid metabolism in mammary epithelial cells of dairy goats (GMECs).
View Article and Find Full Text PDFObjective: To develop and validate a deep learning signature for noninvasive prediction of spread through air spaces (STAS) in clinical stage I lung adenocarcinoma and compare its predictive performance with conventional clinical-semantic model.
Methods: A total of 513 patients with pathologically-confirmed stage I lung adenocarcinoma were retrospectively enrolled and were divided into training cohort (n = 386) and independent validation cohort (n = 127) according to different center. Clinicopathological data were collected and CT semantic features were evaluated.
Postpartum depression and mother-to-infant bonding difficulties (MIBD), two issues crucial to maternal and infant mental health, often coexist and affect each other. Our study aims to dissect their complex relationship through a graphical LASSO network analysis of individual symptoms in 5594 Japanese postpartum women, whose geographical distribution was nationally representative. We identified 'fear', 'enjoyment', 'overwhelm', and 'insomnia' as common bridge symptoms linking postpartum depression and MIBD across three distinct postpartum periods.
View Article and Find Full Text PDFIn recent decades, the threats of ticks and tick-borne diseases (TBDs) increased extensively with environmental change, urbanization, and rapidly changing interactions between human and animals. However, large-scale distribution of tick and TBD risks as well as their relationship with environmental change remain inadequately unclear. Here, we first proposed a "tick-pathogen-habitat-human" model to project the global potential distribution of main pathogenic ticks using a total of 70,714 occurrence records.
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