Publications by authors named "Cho-Ah Lim"
[This corrects the article on p. 432 in vol. 30, PMID: 30065583.
View Article and Find Full Text PDFBackground: Skin hydration is a common problem both in elderly and young people as dry skin may cause irritation, dermatological disorders, and wrinkles. While both genetic and environmental factors seem to influence skin hydration, thorough genetic studies on skin hydration have not yet been conducted.
Objective: We used a genome-wide association study (GWAS) to explore the genetic elements underlying skin hydration by regulating epidermal differentiation and skin barrier function.
[This corrects the article on p. 187 in vol. 29, PMID: 28392646.
View Article and Find Full Text PDFArticle Synopsis
- - Alopecia areata (AA) is a challenging autoimmune disease involving T-cell activity, and systemic immunosuppressive therapies are commonly used for treatment.
- - A study evaluated 29 patients with hard-to-treat AA using low-dose methotrexate (LD-MTX), finding significant regrowth in nearly 90% of participants and a mean dose of 14.48 mg administered twice a week.
- - The results suggest LD-MTX is an effective and tolerable option for treating recalcitrant AA, despite some patients experiencing side effects and a 31% relapse rate among those with over 75% regrowth.
Background: Micro-needle patches have been recently used to increase skin permeability, which improves drug delivery, and for cosmetic purposes. However, these patches may often have limited efficacy due to insufficient skin penetration and reduced compliance caused by discomfort.
Objective: We evaluated the efficacy and the safety of soluble micro-spicule containing epidermal growth factor (MS-EGF) for the treatment of periocular wrinkles.