Enantioselective Molecularly Imprinted Polymer for Tyrosine, Tryptophan, and Phenylalanine, and the Possibility of the Crop-Circle-Like Imprinting.

Molecularly imprinted polymer (L-MIP) for L-tyrosine (L-Tyr) is prepared by the complexation between quaternized poly(4-vinylpyridine/divinylbenzene) (QVP) and poly(acrylamide-co-acrylic acid) (PAmA) in alkaline solution. The L-MIP shows higher enantioselectivity for L-isomers of tyrosine, together with tryptophan (Trp) and phenylalanine (Phe) compared to the D-isomers of them. The sorption isotherms of the three D-enantiomers are converged to one isotherm.

Differences in the gut microbiota between young and elderly persons in Korea.

The gut microbiota differs among countries owing to the prevailing diet composition. For the characterization of the gut microbiota of Koreans at different ages in future studies, e.g.

Impact of decreasing cerebrospinal fluid enterovirus PCR turnaround time on costs and management of children with suspected enterovirus meningitis.

To estimate the impact of implementing in-hospital enterovirus (EV) polymerase chain reaction (PCR) testing of cerebrospinal fluid (CSF) with same-day turn-around-time (TAT) on length-of-stay (LOS), antibiotic use and on cost per patient with suspected EV meningitis, compared with testing at an outside reference laboratory. A model-based analysis using a retrospective cohort of all hospitalized children with CSF EV PCR testing done between November 2013 and 2017. The primary outcome measured was the potential date of discharge if the EV PCR result had been available on the same day.

Effects of glycemic regulation on chronic postischemia pain.

Background: Ischemia-reperfusion (I/R) injuries consist of enhanced oxidative and inflammatory responses along with microvascular dysfunction after prolonged ischemia and reperfusion. Because I/R injuries induce chronic postischemia pain (CPIP) in laboratory animals, it is possible that surgical procedures using prolonged ischemia may result in chronic postoperative pain. Glycemic modulation during ischemia and reperfusion could affect pain after I/R injury because glucose triggers oxidative, inflammatory, and thrombotic reactions, whereas insulin has antioxidative, antiinflammatory, and vasodilatory properties.